Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-Phd
Location 13578..14224 Replicon plasmid unnamed3
Accession NZ_CP114789
Organism Roseibium sp. Sym1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O6760_RS32405 Protein ID WP_062492135.1
Coordinates 13817..14224 (+) Length 136 a.a.

Antitoxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O6760_RS32400 Protein ID WP_082809967.1
Coordinates 13578..13820 (+) Length 81 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6760_RS32385 9785..10978 + 1194 WP_088665297.1 plasmid partitioning protein RepA -
O6760_RS32390 10982..11983 + 1002 WP_152508057.1 plasmid partitioning protein RepB -
O6760_RS32395 12207..13463 + 1257 WP_062492133.1 plasmid replication protein RepC -
O6760_RS32400 13578..13820 + 243 WP_082809967.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O6760_RS32405 13817..14224 + 408 WP_062492135.1 type II toxin-antitoxin system VapC family toxin Toxin
O6760_RS32410 14449..14655 + 207 WP_062492137.1 antitoxin VbhA family protein -
O6760_RS32415 14720..15610 + 891 Protein_17 Fic family protein -
O6760_RS32420 15707..16438 + 732 WP_228148177.1 BID domain-containing protein -
O6760_RS32425 16714..17058 + 345 WP_062492226.1 DUF736 family protein -
O6760_RS32430 17363..17650 + 288 WP_062492139.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..120881 120881


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-118)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(2-50)


Sequences

Toxin        


Download         Length: 136 a.a.        Molecular weight: 15120.26 Da        Isoelectric Point: 5.2058

>T266835 WP_062492135.1 NZ_CP114789:13817-14224 [Roseibium sp. Sym1]
MIYVLDTNVITAARRAERAPKVAAWLSDKPEETLYVSVVTLGEIERGIRLQERRNMDFAKHLRQWLDRTVSMFGDRLLEF
TASDALCWGELSARIGHNGADLMIAAQALTRNGWVVTGNASDFEPTGVQLVDPFV

Download         Length: 408 bp

Antitoxin


Download         Length: 81 a.a.        Molecular weight: 9002.25 Da        Isoelectric Point: 10.4416

>AT266835 WP_082809967.1 NZ_CP114789:13578-13820 [Roseibium sp. Sym1]
MISLQDAKNRFSAVVEAAMAGRPQEVSRRGKPAVVVISSEEYRRLLREAKGRRESFADHVLSFPGEGIERSKVTPRDVEF

Download         Length: 243 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References