Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/ParE-RHH
Location 72194..72732 Replicon plasmid unnamed2
Accession NZ_CP114788
Organism Roseibium sp. Sym1

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag O6760_RS31905 Protein ID WP_075282926.1
Coordinates 72439..72732 (+) Length 98 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag O6760_RS31900 Protein ID WP_075282925.1
Coordinates 72194..72442 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6760_RS31875 68646..68831 + 186 WP_269586475.1 hypothetical protein -
O6760_RS31880 69102..70031 + 930 WP_269586476.1 zincin-like metallopeptidase domain-containing protein -
O6760_RS31885 70755..71072 + 318 WP_075282947.1 DUF736 domain-containing protein -
O6760_RS31890 71160..71420 - 261 WP_269586477.1 WGR domain-containing protein -
O6760_RS31895 71784..71948 + 165 WP_168693765.1 hypothetical protein -
O6760_RS31900 72194..72442 + 249 WP_075282925.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
O6760_RS31905 72439..72732 + 294 WP_075282926.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O6760_RS31910 72766..74685 - 1920 WP_269586478.1 Ti-type conjugative transfer system protein TraG -
O6760_RS31915 74675..74881 - 207 Protein_70 conjugal transfer protein TraD -
O6760_RS31920 74910..75161 - 252 WP_168693775.1 TraC family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..160136 160136


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-90)

Antitoxin

Antitoxin ParD

(1-78)


Sequences

Toxin        


Download         Length: 98 a.a.        Molecular weight: 11307.91 Da        Isoelectric Point: 6.9776

>T266834 WP_075282926.1 NZ_CP114788:72439-72732 [Roseibium sp. Sym1]
MKVLVFSPAAKMDLEHIWDHSVEIWGLDQADRYLDEIRDACFGLASGDRRGRPVDVRAGYLKYATGVHMVYFRDHVDRLE
VIRILHQRQDVSRNLPT

Download         Length: 294 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9159.14 Da        Isoelectric Point: 5.7065

>AT266834 WP_075282925.1 NZ_CP114788:72194-72442 [Roseibium sp. Sym1]
MARNTSVTLGDHFTGFISDQVQTGRYGSASDVVRAGLRLLEEHEAKVKALQDALIAGERSGEPQPFDFDEFKARKRAEYE
SR

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References