Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/-
Location 5903710..5904946 Replicon chromosome
Accession NZ_CP114786
Organism Roseibium sp. Sym1

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O6760_RS27340 Protein ID WP_269582811.1
Coordinates 5904326..5904946 (+) Length 207 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O6760_RS27335 Protein ID WP_269582810.1
Coordinates 5903710..5904276 (+) Length 189 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O6760_RS27315 5899768..5900616 - 849 WP_269582806.1 phosphonate ABC transporter, permease protein PhnE -
O6760_RS27320 5900691..5901608 - 918 WP_269582807.1 phosphonate ABC transporter substrate-binding protein -
O6760_RS27325 5901667..5902500 - 834 WP_269582808.1 phosphonate ABC transporter ATP-binding protein -
O6760_RS27330 5902895..5903521 + 627 WP_269582809.1 chloramphenicol acetyltransferase -
O6760_RS27335 5903710..5904276 + 567 WP_269582810.1 helix-turn-helix domain-containing protein Antitoxin
O6760_RS27340 5904326..5904946 + 621 WP_269582811.1 HD domain-containing protein Toxin
O6760_RS27345 5905082..5905447 + 366 WP_269582812.1 STAS/SEC14 domain-containing protein -
O6760_RS27350 5905669..5906457 - 789 WP_269582813.1 class II glutamine amidotransferase -
O6760_RS27355 5906469..5907935 - 1467 WP_269582814.1 aminotransferase class V-fold PLP-dependent enzyme -
O6760_RS27360 5908041..5908502 + 462 WP_269582815.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

5'-deoxynucleotidase YfbR/HDDC2

(16-156)

Antitoxin

Cro/C1-type helix-turn-helix domain

(16-68)


Sequences

Toxin        


Download         Length: 207 a.a.        Molecular weight: 23145.30 Da        Isoelectric Point: 4.5862

>T266833 WP_269582811.1 NZ_CP114786:5904326-5904946 [Roseibium sp. Sym1]
MTQSDFPSPPDTIDPARLTGILDFLQACEQLKDTLRSGATRKGRPESTAEHSWRLALMILLFERDLKGLDVPKLLKLSLV
HDLGEAISGDVPAPHQTPGDDRAARERRDFQTLCTPLPLDLAAELLALFDEYNAAESLEAQLAKAFDKLETMLQHLLMPT
RDAIFYDFNLGYGRDRTDCSPLTRQIRDRVDVQTRDILIGLEQETA

Download         Length: 621 bp

Antitoxin


Download         Length: 189 a.a.        Molecular weight: 21361.39 Da        Isoelectric Point: 10.7415

>AT266833 WP_269582810.1 NZ_CP114786:5903710-5904276 [Roseibium sp. Sym1]
MPTETAVLNSSLGPSLRRWRVLNRVKQEVLARDLGVSQTRISRWESGQARPEGRHLQKITQLLRARPETASDRALLDLVT
RSGAPVHLVCDLTHRLLAMSPSRAAEWRAPVSEFLNRPLWRFASEGIRSTEHRLADHGWFEPAGPDIVYRTERVDYPEMT
IPESLIRISRLPLSDGSFARLVREEPAA

Download         Length: 567 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References