266830

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) stbDE/ParE-YafN
Location 227143..227665 Replicon plasmid p3045-1
Accession NZ_CP114773
Organism Raoultella planticola strain RP_3045

Toxin (Protein)


Gene name stbE Uniprot ID A0A7H0EVH6
Locus tag O4J57_RS28415 Protein ID WP_014839901.1
Coordinates 227381..227665 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name stbD Uniprot ID A0A7H0EVH5
Locus tag O4J57_RS28410 Protein ID WP_014839900.1
Coordinates 227143..227391 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4J57_RS28400 (O4J57_28395) 224273..225028 - 756 WP_100757158.1 hypothetical protein -
O4J57_RS28405 (O4J57_28400) 225021..226265 - 1245 WP_124053351.1 hypothetical protein -
O4J57_RS28410 (O4J57_28405) 227143..227391 + 249 WP_014839900.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O4J57_RS28415 (O4J57_28410) 227381..227665 + 285 WP_014839901.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O4J57_RS28420 (O4J57_28415) 227856..228332 + 477 WP_042934526.1 hypothetical protein -
O4J57_RS28425 (O4J57_28420) 228338..229015 + 678 WP_042934501.1 hypothetical protein -
O4J57_RS28430 (O4J57_28425) 229032..229373 - 342 WP_233430673.1 DUF2807 domain-containing protein -
O4J57_RS28435 (O4J57_28430) 229356..229751 - 396 Protein_250 cation:proton antiporter -
O4J57_RS28440 (O4J57_28435) 229992..230594 - 603 WP_014839902.1 HAD domain-containing protein -
O4J57_RS28445 (O4J57_28440) 230591..231112 - 522 WP_048336588.1 hypothetical protein -
O4J57_RS28450 (O4J57_28445) 231193..232137 - 945 WP_014839903.1 DsbA family protein -
O4J57_RS28455 (O4J57_28450) 232200..232409 - 210 WP_125316032.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid fosA3 / blaSHV-12 / sul2 / aph(3'')-Ib / aph(6)-Id / qnrS1 / catA2 / aac(3)-IId / sul1 / qacE / blaIMP-4 - 1..260053 260053


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 10866.46 Da        Isoelectric Point: 10.5831

>T266830 WP_014839901.1 NZ_CP114773:227381-227665 [Raoultella planticola]
MTYKLAFNESALKEWKKLGHTIREQFKKKLSERLQNPRVPAAQLHGGKDQYKIKLHGAGYRLVYSVNDEIVTVTVIGVGK
RNNDDIYNATRHRN

Download         Length: 285 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9071.29 Da        Isoelectric Point: 3.8832

>AT266830 WP_014839900.1 NZ_CP114773:227143-227391 [Raoultella planticola]
MAFQVLTTTAASITELKRDPMGTFNAGEGAPVAILNRNEPAFYCVPPALYAQLMEMLEDQELGRIADERIGEDRIEVNID
DL

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A7H0EVH6

Antitoxin

Source ID Structure
AlphaFold DB A0A7H0EVH5

References