Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) shpAB/BrnT-BrnA
Location 4995139..4995718 Replicon chromosome
Accession NZ_CP114772
Organism Raoultella planticola strain RP_3045

Toxin (Protein)


Gene name shpA Uniprot ID -
Locus tag O4J57_RS23730 Protein ID WP_278071913.1
Coordinates 4995431..4995718 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name shpB Uniprot ID A0A485AW76
Locus tag O4J57_RS23725 Protein ID WP_032689635.1
Coordinates 4995139..4995444 (-) Length 102 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4J57_RS23700 (O4J57_23695) 4990348..4991412 - 1065 WP_278071910.1 DUF2955 domain-containing protein -
O4J57_RS23705 (O4J57_23700) 4991402..4992469 - 1068 WP_032689633.1 HlyD family secretion protein -
O4J57_RS23710 (O4J57_23705) 4992476..4992940 - 465 WP_032689634.1 MarR family transcriptional regulator -
O4J57_RS23715 (O4J57_23710) 4993231..4993395 - 165 WP_064497381.1 DUF1127 domain-containing protein -
O4J57_RS23720 (O4J57_23715) 4993573..4994985 + 1413 WP_032697905.1 PLP-dependent aminotransferase family protein -
O4J57_RS23725 (O4J57_23720) 4995139..4995444 - 306 WP_032689635.1 BrnA antitoxin family protein Antitoxin
O4J57_RS23730 (O4J57_23725) 4995431..4995718 - 288 WP_278071913.1 BrnT family toxin Toxin
O4J57_RS23735 (O4J57_23730) 4995960..4996403 - 444 WP_032689637.1 FosA family fosfomycin resistance glutathione transferase -
O4J57_RS23740 (O4J57_23735) 4996397..4997305 - 909 WP_278071914.1 LysR family transcriptional regulator -
O4J57_RS23745 (O4J57_23740) 4997393..4998175 + 783 WP_278071915.1 NAD(P)H-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease toxin, BrnT, of type II toxin-antitoxin system

(7-88)

Antitoxin

BrnA antitoxin of type II toxin-antitoxin system

(39-93)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11182.62 Da        Isoelectric Point: 8.5356

>T266829 WP_278071913.1 NZ_CP114772:c4995718-4995431 [Raoultella planticola]
MPMGFEWYANKATSNLKKHGIRFEEAVLVFDDPQHLSRHDRYENGEYRWQTIELVHGVTVVLVAHSVRFESGTEVIRIIS
ARKADKKERNRYEHG

Download         Length: 288 bp

Antitoxin


Download         Length: 102 a.a.        Molecular weight: 11694.17 Da        Isoelectric Point: 8.4533

>AT266829 WP_032689635.1 NZ_CP114772:c4995444-4995139 [Raoultella planticola]
MNMVKHKRDNPTALTAQREDELNALAKKSDDDIDYSDIPSSDDEPWSEAVRGKFYRPLKTQASVRIDADVMEWLKRPGKG
YQTRLNAILREAMLREQNKKS

Download         Length: 306 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A485AW76

References