Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) /GNAT-DUF1778
Location 5106420..5107219 Replicon chromosome
Accession NZ_CP114771
Organism Endozoicomonas sp. GU-1 strain Ap1-2

Toxin (Protein)


Gene name - Uniprot ID -
Locus tag O3276_RS21355 Protein ID WP_269673118.1
Coordinates 5106707..5107219 (+) Length 171 a.a.

Antitoxin (Protein)


Gene name - Uniprot ID -
Locus tag O3276_RS21350 Protein ID WP_269673117.1
Coordinates 5106420..5106689 (+) Length 90 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3276_RS21325 (O3276_21325) 5102013..5103320 + 1308 WP_269673112.1 tyrosine--tRNA ligase -
O3276_RS21330 (O3276_21330) 5103458..5104036 - 579 WP_269673113.1 AmmeMemoRadiSam system protein A -
O3276_RS21335 (O3276_21335) 5104198..5104977 - 780 WP_269673114.1 AmmeMemoRadiSam system protein B -
O3276_RS21340 (O3276_21340) 5105191..5106090 + 900 WP_269673115.1 AmmeMemoRadiSam system radical SAM enzyme -
O3276_RS21345 (O3276_21345) 5106029..5106292 + 264 WP_269673116.1 hypothetical protein -
O3276_RS21350 (O3276_21350) 5106420..5106689 + 270 WP_269673117.1 DUF1778 domain-containing protein Antitoxin
O3276_RS21355 (O3276_21355) 5106707..5107219 + 513 WP_269673118.1 GNAT family N-acetyltransferase Toxin
O3276_RS21360 (O3276_21360) 5107254..5107685 + 432 WP_269676033.1 YkgJ family cysteine cluster protein -
O3276_RS21365 (O3276_21365) 5107772..5108791 - 1020 WP_269673119.1 alcohol dehydrogenase AdhP -
O3276_RS21370 (O3276_21370) 5109106..5110650 - 1545 WP_269673120.1 maltoporin LamB -
O3276_RS21375 (O3276_21375) 5111004..5111495 - 492 WP_269673121.1 DUF2244 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(90-146)

Antitoxin

Vibrio phage ICP1, Orf50

(5-80)


Sequences

Toxin        


Download         Length: 171 a.a.        Molecular weight: 19108.35 Da        Isoelectric Point: 7.9677

>T266818 WP_269673118.1 NZ_CP114771:5106707-5107219 [Endozoicomonas sp. GU-1]
VELDKGIHDRASFDCGETELNLFIQTQASKHMQAGISRTMVLPASNPFPNQKIPICAFYSITPGSICRDTLPEALVKKLP
RYPVPVFLIAQLAVHREFQGEGLGKICLVNALKYLWEINAHMRAYAIIVDCLTDAAEQFYAKYGFEVLCEHNGKVRMFLP
MKTVARLFSS

Download         Length: 513 bp

Antitoxin


Download         Length: 90 a.a.        Molecular weight: 9998.47 Da        Isoelectric Point: 4.5958

>AT266818 WP_269673117.1 NZ_CP114771:5106420-5106689 [Endozoicomonas sp. GU-1]
MANARLDLRLDEEIKAKAEKASALLGLKSLTEYVVRLMDEDATQVISEYEKMTVENDVFDRFTEACEKAKAPNKALLAAL
TFTEEKSVK

Download         Length: 270 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References