Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/YoeB-RelB
Location 3485191..3485707 Replicon chromosome
Accession NZ_CP114771
Organism Endozoicomonas sp. GU-1 strain Ap1-2

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag O3276_RS14460 Protein ID WP_269671986.1
Coordinates 3485438..3485707 (+) Length 90 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag O3276_RS14455 Protein ID WP_269671985.1
Coordinates 3485191..3485448 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3276_RS14440 (O3276_14440) 3481001..3482068 - 1068 WP_269671982.1 hypothetical protein -
O3276_RS14445 (O3276_14445) 3482085..3482972 - 888 WP_269671983.1 hypothetical protein -
O3276_RS14450 (O3276_14450) 3482987..3485131 - 2145 WP_269671984.1 hypothetical protein -
O3276_RS14455 (O3276_14455) 3485191..3485448 + 258 WP_269671985.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
O3276_RS14460 (O3276_14460) 3485438..3485707 + 270 WP_269671986.1 Txe/YoeB family addiction module toxin Toxin
O3276_RS14465 (O3276_14465) 3485704..3486825 - 1122 WP_269671987.1 hypothetical protein -
O3276_RS14470 (O3276_14470) 3486819..3487343 - 525 WP_269671988.1 hypothetical protein -
O3276_RS14475 (O3276_14475) 3487350..3488147 - 798 WP_269671989.1 hypothetical protein -
O3276_RS14480 (O3276_14480) 3488175..3488780 - 606 WP_269671990.1 hypothetical protein -
O3276_RS14485 (O3276_14485) 3488822..3489193 - 372 WP_269671991.1 hypothetical protein -
O3276_RS14490 (O3276_14490) 3489205..3489564 - 360 WP_269671992.1 hypothetical protein -
O3276_RS14495 (O3276_14495) 3489557..3490162 - 606 WP_269671993.1 hypothetical protein -
O3276_RS14500 (O3276_14500) 3490239..3490430 + 192 WP_269671994.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3464159..3513276 49117


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(9-89)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 90 a.a.        Molecular weight: 10848.46 Da        Isoelectric Point: 9.8419

>T266817 WP_269671986.1 NZ_CP114771:3485438-3485707 [Endozoicomonas sp. GU-1]
MTDKHRLLCWSHNAWNDYLYWQEQDRKTLKRINKLITECLRDPFKGIGKPEPLKGNWQGFWSRRISDEHRLVYQATDARL
IIAACRFHY

Download         Length: 270 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9545.64 Da        Isoelectric Point: 4.5679

>AT266817 WP_269671985.1 NZ_CP114771:3485191-3485448 [Endozoicomonas sp. GU-1]
MKVVSYSEARNNLKSVLDQVAEDASETLIHRRDGQDAVVMSLDSYNSLMETLHLMSSPANAQHLNDSIEQIRTGQVMERG
LLDDR

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References