Detailed information of TA system TA266816

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): PumA-relB/upstrm_HI1419-dnstrm_HI1420
• Location: 3438531..3439197
• Replicon: chromosome
• Accession: NZ_CP114771
• Organism: Endozoicomonas sp. GU-1 strain Ap1-2

Toxin (Protein)

• Gene name: PumA
• Uniprot ID: -
• Locus tag: O3276_RS14215
• Protein ID: WP_269671943.1
• Coordinates: 3438531..3438908 (+)
• Length: 126 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: O3276_RS14220
• Protein ID: WP_269671944.1
• Coordinates: 3438910..3439197 (+)
• Length: 96 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Addiction module killer protein, predicted (29-124)

Antitoxin

• Uncharacterized protein HI1420 (5-92)

Sequences

Toxin

Protein

• Length: 126 a.a.
• Molecular weight: 14379.75 Da
• Isoelectric Point: 9.8022

>T266816 WP_269671943.1 NZ_CP114771:3438531-3438908 [Endozoicomonas sp. GU-1]
MKDLTPGFFPFFVCELEYVSKWIHNSLMYLLKTTDHFEKWLHKLKDKQGKARILASLKLLEQGHIGDWKSVGGKVSELRV
HYGAGYRIYFARQEDVIIVLLNGGDKASQSRDIEKAKAILKNLEA

Nucleotide

• Length: 378 bp

Antitoxin

Protein

• Length: 96 a.a.
• Molecular weight: 10227.72 Da
• Isoelectric Point: 5.8062

>AT266816 WP_269671944.1 NZ_CP114771:3438910-3439197 [Endozoicomonas sp. GU-1]
MSRKLKTFDASEYLDDSETIAEYLNAVIETGDQALLLSAIGDIAKATGMQKIANDSGLGRESLYKALAPGAKPRFDTVFK
ILQALGVSLKISPQH

Nucleotide

• Length: 288 bp