Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 3392370..3392992 Replicon chromosome
Accession NZ_CP114771
Organism Endozoicomonas sp. GU-1 strain Ap1-2

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O3276_RS13920 Protein ID WP_269671893.1
Coordinates 3392370..3392771 (-) Length 134 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O3276_RS13925 Protein ID WP_269671894.1
Coordinates 3392771..3392992 (-) Length 74 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3276_RS13905 (O3276_13905) 3389052..3389246 - 195 WP_269671891.1 hypothetical protein -
O3276_RS13910 (O3276_13910) 3389304..3389399 - 96 WP_269675989.1 hypothetical protein -
O3276_RS13915 (O3276_13915) 3389634..3392030 - 2397 WP_269671892.1 exonuclease domain-containing protein -
O3276_RS13920 (O3276_13920) 3392370..3392771 - 402 WP_269671893.1 PIN domain-containing protein Toxin
O3276_RS13925 (O3276_13925) 3392771..3392992 - 222 WP_269671894.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
O3276_RS13930 (O3276_13930) 3393067..3393390 + 324 WP_269671895.1 hypothetical protein -
O3276_RS13935 (O3276_13935) 3393511..3394764 + 1254 WP_269671896.1 ISL3 family transposase -
O3276_RS13940 (O3276_13940) 3395209..3395484 - 276 WP_163370563.1 type II toxin-antitoxin system RelE/ParE family toxin -
O3276_RS13945 (O3276_13945) 3395481..3395729 - 249 WP_257266787.1 ribbon-helix-helix protein, CopG family -
O3276_RS13950 (O3276_13950) 3396115..3396705 + 591 WP_269671897.1 nucleotidyltransferase domain-containing protein -
O3276_RS13955 (O3276_13955) 3396702..3396887 + 186 WP_269671898.1 hypothetical protein -
O3276_RS13960 (O3276_13960) 3396996..3397397 - 402 WP_269671899.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 3389634..3427688 38054


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 134 a.a.        Molecular weight: 14996.04 Da        Isoelectric Point: 6.3303

>T266814 WP_269671893.1 NZ_CP114771:c3392771-3392370 [Endozoicomonas sp. GU-1]
MAEYMVDTDICIAVLKHNRPVIDKFIEHQGKVYVSSISCYELQFGIEKGDPEHRQGKESKLSFFLEGVNVIDFDGAAARE
SAKVREELQRGQQIGAYDTLLAAHARSRGMVMVTHNQREFSRVPGLQLADWLG

Download         Length: 402 bp

Antitoxin


Download         Length: 74 a.a.        Molecular weight: 8622.85 Da        Isoelectric Point: 4.3449

>AT266814 WP_269671894.1 NZ_CP114771:c3392992-3392771 [Endozoicomonas sp. GU-1]
METSVFFNNKTQAVRIPKELAFPDTVKRVMVRKEGKAIILTPIEDYWETFLAMEPIDDFPEREQPACQDREDF

Download         Length: 222 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References