Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 270721..271252 Replicon chromosome
Accession NZ_CP114771
Organism Endozoicomonas sp. GU-1 strain Ap1-2

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O3276_RS01280 Protein ID WP_163373295.1
Coordinates 270721..271008 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag O3276_RS01285 Protein ID WP_163373296.1
Coordinates 270998..271252 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3276_RS01245 (O3276_01245) 266257..266568 - 312 WP_269673999.1 HigA family addiction module antitoxin -
O3276_RS01250 (O3276_01250) 266844..267305 - 462 WP_269674000.1 hypothetical protein -
O3276_RS01255 (O3276_01255) 267356..267967 - 612 WP_269674001.1 hypothetical protein -
O3276_RS01260 (O3276_01260) 268004..268975 - 972 WP_269674002.1 IS66 family transposase -
O3276_RS01265 (O3276_01265) 268986..269627 - 642 WP_269674003.1 transposase -
O3276_RS01270 (O3276_01270) 269759..270127 - 369 WP_269674004.1 DUF3768 domain-containing protein -
O3276_RS01275 (O3276_01275) 270253..270729 + 477 WP_269674005.1 hypothetical protein -
O3276_RS01280 (O3276_01280) 270721..271008 - 288 WP_163373295.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O3276_RS01285 (O3276_01285) 270998..271252 - 255 WP_163373296.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O3276_RS01290 (O3276_01290) 271327..273188 + 1862 Protein_246 phage terminase large subunit family protein -
O3276_RS01295 (O3276_01295) 273194..273394 + 201 WP_269674006.1 hypothetical protein -
O3276_RS01300 (O3276_01300) 273397..274866 + 1470 WP_269674007.1 phage portal protein -
O3276_RS01305 (O3276_01305) 274856..275866 + 1011 WP_269674008.1 Clp protease ClpP -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(14-76)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11271.15 Da        Isoelectric Point: 10.6676

>T266807 WP_163373295.1 NZ_CP114771:c271008-270721 [Endozoicomonas sp. GU-1]
MTYELDFSALAWKEWQKLNSTVREQFKAKLRKRLENPKVSKDKLSGQKDCYKIKLRNSGYRLVYQVLDDVVVVFVISVGK
RERSEAYKAAQKRLR

Download         Length: 288 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9255.59 Da        Isoelectric Point: 4.3304

>AT266807 WP_163373296.1 NZ_CP114771:c271252-270998 [Endozoicomonas sp. GU-1]
MASVHPILADVSAGISELKKNPMAVLKEANGETVAILNRNQPVFYAVPAHVYEAMLDALDDLELAAIVEERKNDERIRVN
IDDL

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References