Detailed information of TA system
Overview
TA module
| Type | II | Classification (family/domain) | pmenTA/darT(toxin) |
| Location | 3868947..3869692 | Replicon | chromosome |
| Accession | NZ_CP114600 | ||
| Organism | Xanthomonas oryzae pv. oryzae strain LA20 | ||
Toxin (Protein)
| Gene name | pmenT | Uniprot ID | - |
| Locus tag | O5966_RS18045 | Protein ID | WP_205420989.1 |
| Coordinates | 3868947..3869276 (+) | Length | 110 a.a. |
Antitoxin (Protein)
| Gene name | pmenA | Uniprot ID | - |
| Locus tag | O5966_RS18050 | Protein ID | WP_237384720.1 |
| Coordinates | 3869273..3869692 (+) | Length | 140 a.a. |
Genomic Context
| Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| O5966_RS18015 (O5966_18015) | 3864077..3864748 | + | 672 | WP_011407759.1 | class I SAM-dependent methyltransferase | - |
| O5966_RS18025 (O5966_18025) | 3865051..3865842 | - | 792 | WP_171970779.1 | polysaccharide deacetylase family protein | - |
| O5966_RS18030 (O5966_18030) | 3865888..3866814 | + | 927 | WP_011257932.1 | Grx4 family monothiol glutaredoxin | - |
| O5966_RS18035 (O5966_18035) | 3867146..3867481 | + | 336 | WP_011407757.1 | DarT ssDNA thymidine ADP-ribosyltransferase family protein | - |
| O5966_RS18040 (O5966_18040) | 3867525..3868844 | - | 1320 | WP_269441315.1 | IS701 family transposase | - |
| O5966_RS18045 (O5966_18045) | 3868947..3869276 | + | 330 | WP_205420989.1 | DUF4433 domain-containing protein | Toxin |
| O5966_RS18050 (O5966_18050) | 3869273..3869692 | + | 420 | WP_237384720.1 | macro domain-containing protein | Antitoxin |
| O5966_RS18055 (O5966_18055) | 3869744..3870711 | + | 968 | WP_269441316.1 | IS5-like element ISXo1 family transposase | - |
| O5966_RS18060 (O5966_18060) | 3870903..3871871 | + | 969 | WP_011258188.1 | IS5-like element ISXo1 family transposase | - |
| O5966_RS18065 (O5966_18065) | 3872024..3872662 | + | 639 | WP_011407753.1 | phosphate phosphatase | - |
| O5966_RS18070 (O5966_18070) | 3872700..3873934 | - | 1235 | Protein_3461 | ISL3-like element ISXoo13 family transposase | - |
| O5966_RS18075 (O5966_18075) | 3874236..3874562 | + | 327 | Protein_3462 | hypothetical protein | - |
Associated MGEs
| MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
|---|---|---|---|---|---|---|---|
| - | inside | IScluster/Tn | - | - | 3867525..3873934 | 6409 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 110 a.a. Molecular weight: 13159.89 Da Isoelectric Point: 7.1161
>T266788 WP_205420989.1 NZ_CP114600:3868947-3869276 [Xanthomonas oryzae pv. oryzae]
MHHVAERRWPFLFTDSHAYCQLASFYSELSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR
MHHVAERRWPFLFTDSHAYCQLASFYSELSDLDKIDWPLLQARDFRRDPDDPAKFERYQAEALIHRHLPLDGLRGIVCHT
DGLKQTIERQLQERNLKLPVHTRTDWYFR
Download Length: 330 bp
Antitoxin
Download Length: 140 a.a. Molecular weight: 15621.05 Da Isoelectric Point: 6.4733
>AT266788 WP_237384720.1 NZ_CP114600:3869273-3869692 [Xanthomonas oryzae pv. oryzae]
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQLRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL
MITFTQGNLLESGAEALVNTVNTVGVMGKGIALMFKERFKENFLRYAAACKDNQLRIGKIFVTEVNELDGPRWIINFPTK
QHWRGDSRIEWITEGLQDLHRFLIENKVKSIAIPPLGAGNGGLDWAEVRPLIEEVLGNL
Download Length: 420 bp
Similar Proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|
Structures
Toxin
| Source | ID | Structure |
|---|
Antitoxin
| Source | ID | Structure |
|---|