Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) rlegTA/AbiEii-AbiEi
Location 1553612..1555131 Replicon chromosome
Accession NZ_CP114600
Organism Xanthomonas oryzae pv. oryzae strain LA20

Toxin (Protein)


Gene name rlegT Uniprot ID A0A0K0GMB6
Locus tag O5966_RS07405 Protein ID WP_011259680.1
Coordinates 1554208..1555131 (+) Length 308 a.a.

Antitoxin (Protein)


Gene name rlegA Uniprot ID A0A854CLN1
Locus tag O5966_RS07400 Protein ID WP_011409027.1
Coordinates 1553612..1554211 (+) Length 200 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O5966_RS07365 (O5966_07365) 1549280..1549816 - 537 WP_024743012.1 lipocalin family protein -
O5966_RS07375 (O5966_07375) 1550193..1550567 - 375 WP_237384745.1 hypothetical protein -
O5966_RS07380 (O5966_07380) 1550548..1550838 - 291 WP_011409031.1 hypothetical protein -
O5966_RS07385 (O5966_07385) 1551337..1552368 + 1032 WP_117231631.1 IS630 family transposase -
O5966_RS07390 (O5966_07390) 1552350..1552925 - 576 WP_080493559.1 BrxE family protein -
O5966_RS07395 (O5966_07395) 1552957..1553247 - 291 WP_233282844.1 FaeA/PapI family transcriptional regulator -
O5966_RS07400 (O5966_07400) 1553612..1554211 + 600 WP_011409027.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
O5966_RS07405 (O5966_07405) 1554208..1555131 + 924 WP_011259680.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
O5966_RS07410 (O5966_07410) 1555211..1555681 - 471 WP_228329666.1 helix-turn-helix domain-containing protein -
O5966_RS07415 (O5966_07415) 1556147..1556389 + 243 WP_011259679.1 hypothetical protein -
O5966_RS07420 (O5966_07420) 1556814..1557323 + 510 WP_011259678.1 hypothetical protein -
O5966_RS07425 (O5966_07425) 1557340..1557872 - 533 Protein_1416 methyltransferase domain-containing protein -
O5966_RS07430 (O5966_07430) 1557892..1559268 - 1377 Protein_1417 IS5 family transposase -
O5966_RS07435 (O5966_07435) 1559380..1559532 - 153 Protein_1418 SAM-dependent methyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 1551394..1552368 974


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(41-269)

Antitoxin

Transcriptional regulator, AbiEi antitoxin

(7-52)


Sequences

Toxin        


Download         Length: 308 a.a.        Molecular weight: 34114.16 Da        Isoelectric Point: 5.4588

>T266786 WP_011259680.1 NZ_CP114600:1554208-1555131 [Xanthomonas oryzae pv. oryzae]
MNEPDKSRRTVAASVRARLLNKARAERLDFNLLLTRYALERVLYRLSVSEQQGQFLLKGALLFDIWFDIPHRPTHDADLL
GFGSTEIPHLEDLFRRISQIASDDGIVFQADSVKAAEIRKEANYAGVRVTMIGLLDGARCTVQIDIGFGDAVTPGPDNVQ
YPVILDGMPQPQLRVYPRYTVVAEKLEAMVKLGILNSRMKDYFDLWVLAGHSDFDGAVLATAIRATFECRGTAIPPGAPL
GLTDEFGLDEQKTKQWQAFLRKNTLEPMPLTTVIEALREFVLPVLAALAAGEGFDRQWRAGAGWDAA

Download         Length: 924 bp

Antitoxin


Download         Length: 200 a.a.        Molecular weight: 22037.74 Da        Isoelectric Point: 10.1240

>AT266786 WP_011409027.1 NZ_CP114600:1553612-1554211 [Xanthomonas oryzae pv. oryzae]
MDTTVDKLLELVRTRGLLRPHDLAPLGIPRVALTRAVRRGQLERVGRGLYGLVARPVSAHGTLAEVARRVPKGVVCLLSA
LRVHDLTTQAPFEVWLAIDNKAAAPKLDYPPLRLVRFSGPALSEGVEEHVVDGVPVHVTSVAKTVADCFKYRNKIGIDVA
LEALREAWVARRMTSDEIWHYAKIDRVANVMRPYLESLA

Download         Length: 600 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K0GMB6

Antitoxin

Source ID Structure
AlphaFold DB A0A854CLN1

References