266784

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) parDE/RHH(antitoxin)
Location 3633080..3633611 Replicon chromosome
Accession NZ_CP114599
Organism Phenylobacterium sp. NIBR 498073

Toxin (Protein)


Gene name parE Uniprot ID -
Locus tag O4N75_RS18160 Protein ID WP_269626852.1
Coordinates 3633321..3633611 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name parD Uniprot ID -
Locus tag O4N75_RS18155 Protein ID WP_269626851.1
Coordinates 3633080..3633313 (+) Length 78 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4N75_RS18140 (O4N75_18140) 3628987..3629904 + 918 WP_269626848.1 ABC transporter ATP-binding protein -
O4N75_RS18145 (O4N75_18145) 3629954..3631087 + 1134 WP_269626849.1 ABC transporter permease -
O4N75_RS18150 (O4N75_18150) 3631184..3633007 + 1824 WP_269626850.1 DUF885 family protein -
O4N75_RS18155 (O4N75_18155) 3633080..3633313 + 234 WP_269626851.1 type II toxin-antitoxin system ParD family antitoxin Antitoxin
O4N75_RS18160 (O4N75_18160) 3633321..3633611 + 291 WP_269626852.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O4N75_RS18165 (O4N75_18165) 3633653..3636187 + 2535 WP_269626853.1 helicase-related protein -
O4N75_RS18170 (O4N75_18170) 3636184..3636465 + 282 WP_269626854.1 RNA-binding S4 domain-containing protein -
O4N75_RS18175 (O4N75_18175) 3636487..3637257 + 771 WP_269626855.1 pseudouridine synthase -
O4N75_RS18180 (O4N75_18180) 3637351..3637770 + 420 WP_269626856.1 DUF805 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Antitoxin ParD

(1-76)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11046.62 Da        Isoelectric Point: 7.5179

>T266784 WP_269626852.1 NZ_CP114599:3633321-3633611 [Phenylobacterium sp. NIBR 498073]
MVRYILSPKAKADLSEIWDYGADHWGVDRATDYIRDIQRAIEHAAAHPLRGRACDEVRAGYFKVSVGSHLLFHRLVDDVL
DVVRVLHQRMDVGRHL

Download         Length: 291 bp

Antitoxin


Download         Length: 78 a.a.        Molecular weight: 8387.43 Da        Isoelectric Point: 4.6096

>AT266784 WP_269626851.1 NZ_CP114599:3633080-3633313 [Phenylobacterium sp. NIBR 498073]
MGKNTSISLGEHFAAFIETEVAKGRYASASEVVRASLRLLEEREAQLEALRLALIEGEESGPSTPFDFDAFIASKRA

Download         Length: 234 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References