Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2009061..2009332 Replicon chromosome
Accession NZ_CP114592
Organism Escherichia coli strain WEC

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2009191..2009294 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2009061..2009332 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3296_RS09715 2005616..2006278 - 663 WP_000944256.1 exodeoxyribonuclease X -
O3296_RS09720 2006302..2006958 - 657 WP_000011659.1 carbon-nitrogen hydrolase family protein YobB -
O3296_RS09725 2007060..2007290 - 231 WP_000916763.1 DNA polymerase III subunit theta -
O3296_RS09730 2007429..2007803 + 375 WP_000168747.1 CopC domain-containing protein YobA -
O3296_RS09735 2007807..2008679 + 873 WP_001569950.1 copper homeostasis membrane protein CopD -
O3296_RS09740 2008692..2009033 + 342 WP_000976472.1 YebY family protein -
- 2009061..2009332 - 272 - - Antitoxin
- 2009191..2009294 + 104 - - Toxin
O3296_RS09745 2009429..2010085 + 657 WP_063625304.1 protein-serine/threonine phosphatase -
O3296_RS09750 2010086..2010277 - 192 WP_001296140.1 YebW family protein -
O3296_RS09755 2010382..2010618 - 237 WP_001295499.1 YebV family protein -
O3296_RS09760 2010736..2012175 - 1440 WP_000057022.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T266765 NZ_CP114592:2009191-2009294 [Escherichia coli]
GGCAAGGCAACTAAGTCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT266765 NZ_CP114592:c2009332-2009061 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAAATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGACTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References