Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-RelB
Location 329528..330087 Replicon plasmid unnamed
Accession NZ_CP114587
Organism Salinivibrio kushneri strain TGB4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O4598_RS14300 Protein ID WP_269600714.1
Coordinates 329809..330087 (+) Length 93 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag O4598_RS14295 Protein ID WP_062907370.1
Coordinates 329528..329812 (+) Length 95 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4598_RS14275 (O4598_14275) 324894..325817 - 924 WP_269600711.1 LysR family transcriptional regulator -
O4598_RS14280 (O4598_14280) 326041..327672 + 1632 WP_269600712.1 alpha-glucosidase -
O4598_RS14285 (O4598_14285) 327782..328303 - 522 WP_269600713.1 GNAT family N-acetyltransferase -
O4598_RS14290 (O4598_14290) 328696..329432 + 737 Protein_303 ISAs1 family transposase -
O4598_RS14295 (O4598_14295) 329528..329812 + 285 WP_062907370.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
O4598_RS14300 (O4598_14300) 329809..330087 + 279 WP_269600714.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O4598_RS14305 (O4598_14305) 330208..330507 - 300 WP_269601154.1 type II toxin-antitoxin system RelE/ParE family toxin -
O4598_RS14310 (O4598_14310) 330508..330777 - 270 WP_269600715.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
O4598_RS14315 (O4598_14315) 330974..331195 + 222 WP_007113097.1 hypothetical protein -
O4598_RS14320 (O4598_14320) 331188..331478 + 291 WP_269600717.1 type II toxin-antitoxin system RelE/ParE family toxin -
O4598_RS14325 (O4598_14325) 331523..332278 - 756 WP_269600719.1 abortive infection family protein -
O4598_RS14330 (O4598_14330) 333068..335071 + 2004 WP_269600720.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..562514 562514
- flank IS/Tn - - 328696..329349 653


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(2-88)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(5-70)


Sequences

Toxin        


Download         Length: 93 a.a.        Molecular weight: 10922.63 Da        Isoelectric Point: 4.3535

>T266753 WP_269600714.1 NZ_CP114587:329809-330087 [Salinivibrio kushneri]
MILWEEESLNDREKIFEFLYGFNPEVAEKTDSFIEEKVDNLLEQPLMGVQRDSIRGRLLIIPEISMIVSYWVEGDIIRVM
RVLHQKQKLPTD

Download         Length: 279 bp

Antitoxin


Download         Length: 95 a.a.        Molecular weight: 11039.37 Da        Isoelectric Point: 9.2167

>AT266753 WP_062907370.1 NZ_CP114587:329528-329812 [Salinivibrio kushneri]
MDTRIQFRVDEETKRLAQQMAESQGRTLSDACRELTEQLAEQQRKTLSHDAWLTEQVNLAFEKFDSGKSVFVEHQAAKSR
MEERKARIRNRGKQ

Download         Length: 285 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References