Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/Doc(toxin)
Location 1659156..1659712 Replicon chromosome
Accession NZ_CP114586
Organism Salinivibrio kushneri strain TGB4

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag O4598_RS07865 Protein ID WP_077523282.1
Coordinates 1659156..1659542 (-) Length 129 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag O4598_RS07870 Protein ID WP_077487035.1
Coordinates 1659542..1659712 (-) Length 57 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4598_RS07835 (O4598_07835) 1654511..1655452 - 942 WP_077458557.1 ACP S-malonyltransferase -
O4598_RS07840 (O4598_07840) 1655471..1656430 - 960 WP_069362213.1 beta-ketoacyl-ACP synthase III -
O4598_RS07845 (O4598_07845) 1656439..1657461 - 1023 WP_069362212.1 phosphate acyltransferase PlsX -
O4598_RS07850 (O4598_07850) 1657471..1657641 - 171 WP_046075434.1 50S ribosomal protein L32 -
O4598_RS07855 (O4598_07855) 1657647..1658177 - 531 WP_069362211.1 23S rRNA accumulation protein YceD -
O4598_RS07860 (O4598_07860) 1658503..1659096 + 594 WP_077487031.1 nucleoside triphosphate pyrophosphatase -
O4598_RS07865 (O4598_07865) 1659156..1659542 - 387 WP_077523282.1 type II toxin-antitoxin system death-on-curing family toxin Toxin
O4598_RS07870 (O4598_07870) 1659542..1659712 - 171 WP_077487035.1 acetyltransferase Antitoxin
O4598_RS07875 (O4598_07875) 1659796..1660521 - 726 WP_269599152.1 HAD-IA family hydrolase -
O4598_RS07880 (O4598_07880) 1660606..1661556 - 951 WP_269599154.1 23S rRNA pseudouridine(955/2504/2580) synthase RluC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Death on curing protein

(1-126)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 129 a.a.        Molecular weight: 13903.89 Da        Isoelectric Point: 3.9499

>T266748 WP_077523282.1 NZ_CP114586:c1659542-1659156 [Salinivibrio kushneri]
MDIICFPFERVIEINAFILASGPGMQGAVDLGKLQGALSRIDNAIIYDGLDDVFEIAAKYTACIAVAHALPDANKRTGLA
VALEYLSLNDFEIVHDNDLLADAVRDLVLGEISELDFADVLYAQYARV

Download         Length: 387 bp

Antitoxin


Download         Length: 57 a.a.        Molecular weight: 6384.51 Da        Isoelectric Point: 11.0888

>AT266748 WP_077487035.1 NZ_CP114586:c1659712-1659542 [Salinivibrio kushneri]
MNRKIENYGVQSIQRPKIKAKKSIDLSGDLGRQIIKSETKLALRTHANTFKKLADM

Download         Length: 171 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References