Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relB-yefM/YoeB-RelB
Location 1190367..1190883 Replicon chromosome
Accession NZ_CP114584
Organism Salinivibrio proteolyticus strain TGB10

Toxin (Protein)


Gene name relB Uniprot ID A0A1V3HGW7
Locus tag N7E60_RS05760 Protein ID WP_025744833.1
Coordinates 1190620..1190883 (+) Length 88 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag N7E60_RS05755 Protein ID WP_269598351.1
Coordinates 1190367..1190627 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E60_RS05715 (N7E60_05715) 1185636..1185905 - 270 Protein_1086 IS110 family transposase -
N7E60_RS05720 (N7E60_05720) 1185936..1186277 + 342 WP_269598346.1 GNAT family N-acetyltransferase -
N7E60_RS05725 (N7E60_05725) 1186249..1187045 + 797 WP_269597063.1 IS5 family transposase -
N7E60_RS05730 (N7E60_05730) 1187118..1187273 + 156 WP_269598347.1 GNAT family N-acetyltransferase -
N7E60_RS05735 (N7E60_05735) 1187435..1188385 + 951 WP_269598348.1 prolyl aminopeptidase -
N7E60_RS05740 (N7E60_05740) 1188747..1189085 + 339 WP_269598349.1 hypothetical protein -
N7E60_RS05745 (N7E60_05745) 1189141..1189689 + 549 WP_096627911.1 GNAT family protein -
N7E60_RS05750 (N7E60_05750) 1189711..1190208 + 498 WP_269598350.1 ASCH domain-containing protein -
N7E60_RS05755 (N7E60_05755) 1190367..1190627 + 261 WP_269598351.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
N7E60_RS05760 (N7E60_05760) 1190620..1190883 + 264 WP_025744833.1 Txe/YoeB family addiction module toxin Toxin
N7E60_RS05765 (N7E60_05765) 1191231..1191626 + 396 WP_269598352.1 hypothetical protein -
N7E60_RS05770 (N7E60_05770) 1191697..1192095 - 399 WP_069590096.1 acyl-CoA thioester hydrolase YciA -
N7E60_RS05775 (N7E60_05775) 1192189..1192731 - 543 WP_077640746.1 septation protein A -
N7E60_RS05780 (N7E60_05780) 1192882..1194225 - 1344 WP_069590100.1 sodium-dependent transporter -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(8-87)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-73)


Sequences

Toxin        


Download         Length: 88 a.a.        Molecular weight: 10446.91 Da        Isoelectric Point: 9.0258

>T266743 WP_025744833.1 NZ_CP114584:1190620-1190883 [Salinivibrio proteolyticus]
MSSRLLCWTDDAWRDYVYWQSQDRKTLKRINKLILDVKRTPFEGIGKPEALKENLTGFWSRRIDDTNRLVYAVDDTSITI
LSCRYHY

Download         Length: 264 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9642.88 Da        Isoelectric Point: 4.5983

>AT266743 WP_269598351.1 NZ_CP114584:1190367-1190627 [Salinivibrio proteolyticus]
MKIISFTEARNGLKTVLDGVVDDADTTIITRRDAEDAVVMSLDYYNSLMETVHLLRSPANAEHLNRSITQYKMGKAMEHA
LVDSDE

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1V3HGW7

Antitoxin

Source ID Structure

References