Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/Phd(antitoxin)
Location 940475..941019 Replicon chromosome
Accession NZ_CP114584
Organism Salinivibrio proteolyticus strain TGB10

Toxin (Protein)


Gene name relE Uniprot ID A0A1V3HA63
Locus tag N7E60_RS04610 Protein ID WP_021024563.1
Coordinates 940720..941019 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A1V3HAB7
Locus tag N7E60_RS04605 Protein ID WP_025744793.1
Coordinates 940475..940732 (+) Length 86 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
N7E60_RS04590 (N7E60_04590) 935752..938901 + 3150 WP_269598238.1 multidrug efflux RND transporter permease subunit -
N7E60_RS04595 (N7E60_04595) 938984..939679 - 696 WP_077640455.1 7-cyano-7-deazaguanine synthase QueC -
N7E60_RS04600 (N7E60_04600) 939861..940385 + 525 WP_269598239.1 RES family NAD+ phosphorylase -
N7E60_RS04605 (N7E60_04605) 940475..940732 + 258 WP_025744793.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
N7E60_RS04610 (N7E60_04610) 940720..941019 + 300 WP_021024563.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
N7E60_RS04615 (N7E60_04615) 941095..941529 - 435 WP_231637397.1 thioesterase family protein -
N7E60_RS04620 (N7E60_04620) 941773..943155 + 1383 WP_269598240.1 ATP-dependent RNA helicase DbpA -
N7E60_RS04625 (N7E60_04625) 943195..944019 + 825 WP_269598241.1 phosphotransferase -
N7E60_RS04630 (N7E60_04630) 944099..944593 + 495 WP_269598242.1 DUF1003 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-91)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-68)


Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11335.15 Da        Isoelectric Point: 4.5994

>T266742 WP_021024563.1 NZ_CP114584:940720-941019 [Salinivibrio proteolyticus]
MAQIVWTEPALADLNDVAEYVALDNLVAAKALVQAAFTAVERLVLFPDSGRVPPELPHLNYREVVVNPCRIFYKQEEDTV
FILFVMRSEQDLRKFLLSR

Download         Length: 300 bp

Antitoxin


Download         Length: 86 a.a.        Molecular weight: 9798.45 Da        Isoelectric Point: 9.5940

>AT266742 WP_025744793.1 NZ_CP114584:940475-940732 [Salinivibrio proteolyticus]
MKVELVTTLKRQATKILSELKANKEPVLITEHGKPSAYLLSVDDYELMQRRLAILEGIARGERAITEEKLLSHHDAKEQM
SRWLK

Download         Length: 258 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1V3HA63

Antitoxin

Source ID Structure
AlphaFold DB A0A1V3HAB7

References