Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 3483412..3483949 Replicon chromosome
Accession NZ_CP114576
Organism Legionella pneumophila strain H3

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag LpnH3D14_RS15760 Protein ID WP_042234319.1
Coordinates 3483412..3483708 (-) Length 99 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag LpnH3D14_RS15765 Protein ID WP_027266056.1
Coordinates 3483698..3483949 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
LpnH3D14_RS15735 (LpnH3D14_03170) 3479622..3480515 - 894 WP_042234326.1 hypothetical protein -
LpnH3D14_RS15740 (LpnH3D14_03171) 3480783..3480974 + 192 WP_011947807.1 hypothetical protein -
LpnH3D14_RS15745 3481121..3481225 - 105 Protein_3092 lytic murein transglycosylase -
LpnH3D14_RS15750 (LpnH3D14_03172) 3481319..3482482 - 1164 WP_014842907.1 tetratricopeptide repeat protein -
LpnH3D14_RS15755 (LpnH3D14_03173) 3482841..3483323 - 483 WP_014842908.1 hypothetical protein -
LpnH3D14_RS15760 (LpnH3D14_03174) 3483412..3483708 - 297 WP_042234319.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
LpnH3D14_RS15765 (LpnH3D14_03175) 3483698..3483949 - 252 WP_027266056.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
LpnH3D14_RS15770 3484037..3484237 - 201 WP_236708780.1 hypothetical protein -
LpnH3D14_RS15775 (LpnH3D14_03177) 3484815..3485954 - 1140 WP_129317146.1 DUF3800 domain-containing protein -
LpnH3D14_RS15780 (LpnH3D14_03178) 3486072..3486629 - 558 WP_129317147.1 recombinase family protein -
LpnH3D14_RS15785 3486717..3486857 + 141 WP_154231193.1 hypothetical protein -
LpnH3D14_RS15790 (LpnH3D14_03179) 3486882..3487385 - 504 WP_042234312.1 hypothetical protein -
LpnH3D14_RS15795 (LpnH3D14_03180) 3487495..3488541 - 1047 WP_027219936.1 FAD-dependent oxidoreductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(6-85)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(8-60)


Sequences

Toxin        


Download         Length: 99 a.a.        Molecular weight: 11424.29 Da        Isoelectric Point: 10.5027

>T266738 WP_042234319.1 NZ_CP114576:c3483708-3483412 [Legionella pneumophila]
MIYELHFHPLALKEWKKLGKNLQEEFKKVLKRRLENPHVASAGLRGSLKNCYKIKLRQSGYRLVYQVNDNKLIVTVIAVG
KRNKNVVYGDADNRQEDS

Download         Length: 297 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9271.70 Da        Isoelectric Point: 5.0359

>AT266738 WP_027266056.1 NZ_CP114576:c3483949-3483698 [Legionella pneumophila]
MQTLFATQVASISELKKNPTKLINDAHGKPVAILNHNTAAAYLIPVETFEKLMDLIDENELHKIVEERLSAPFTSIKVNI
DDL

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References