266720

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2624861..2625460 Replicon chromosome
Accession NZ_CP114551
Organism Xylella fastidiosa subsp. pauca strain OLI17A

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O4443_RS11945 Protein ID WP_228762756.1
Coordinates 2625173..2625460 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q9P9V8
Locus tag O4443_RS11940 Protein ID WP_010895177.1
Coordinates 2624861..2625169 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4443_RS11905 (O4443_11905) 2621445..2622206 - 762 WP_010895174.1 Bax inhibitor-1/YccA family protein -
O4443_RS11930 (O4443_11930) 2623007..2623201 + 195 WP_069107173.1 hypothetical protein -
O4443_RS11935 (O4443_11935) 2623401..2624795 + 1395 WP_109161026.1 hypothetical protein -
O4443_RS11940 (O4443_11940) 2624861..2625169 - 309 WP_010895177.1 putative addiction module antidote protein Antitoxin
O4443_RS11945 (O4443_11945) 2625173..2625460 - 288 WP_228762756.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O4443_RS11950 (O4443_11950) 2625556..2626326 + 771 WP_010895179.1 hypothetical protein -
O4443_RS11955 (O4443_11955) 2626326..2626592 + 267 WP_023907141.1 hypothetical protein -
O4443_RS11960 (O4443_11960) 2627051..2627444 - 394 Protein_2333 DUF596 domain-containing protein -
O4443_RS11965 (O4443_11965) 2627456..2627758 - 303 Protein_2334 DUF769 domain-containing protein -
O4443_RS11970 (O4443_11970) 2627984..2628367 - 384 WP_031338086.1 DUF596 domain-containing protein -
O4443_RS11975 (O4443_11975) 2628379..2628720 - 342 Protein_2336 DUF769 domain-containing protein -
O4443_RS11980 (O4443_11980) 2628880..2629272 - 393 WP_167701479.1 DUF596 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2623401..2626592 3191


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(1-94)

Antitoxin

Uncharacterized protein HI1420

(15-100)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 10939.63 Da        Isoelectric Point: 10.3074

>T266720 WP_228762756.1 NZ_CP114551:c2625460-2625173 [Xylella fastidiosa subsp. pauca]
VKRLEEFSDWLKGLKDGLARQRLIKRLRKVQLGNFGDVQPVGEGVFEMREHFGPGWRMYYVQRGSFLIVMLGGGDKSTQQ
SDIRRAIELAKSLED

Download         Length: 288 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 11038.60 Da        Isoelectric Point: 4.6561

>AT266720 WP_010895177.1 NZ_CP114551:c2625169-2624861 [Xylella fastidiosa subsp. pauca]
VTITKKINVSELPEFDAAEYLSSEEEVAAYLTAVLEENDPALLAAALGDIARSRGMSQIAKDSGITREGLYKALRPGSEP
RFDTISRVCTALGIRLVAQPMR

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A1S0V409

References