Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 1699506..1700037 Replicon chromosome
Accession NZ_CP114551
Organism Xylella fastidiosa subsp. pauca strain OLI17A

Toxin (Protein)


Gene name relE Uniprot ID A0A1L2ALG3
Locus tag O4443_RS07985 Protein ID WP_060872142.1
Coordinates 1699506..1699787 (-) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID A0A1L2ALQ3
Locus tag O4443_RS07990 Protein ID WP_060872141.1
Coordinates 1699774..1700037 (-) Length 88 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4443_RS07955 (O4443_07955) 1695359..1697239 + 1881 WP_088372102.1 phage major capsid protein -
O4443_RS07960 (O4443_07960) 1697257..1697517 + 261 WP_060872391.1 hypothetical protein -
O4443_RS07965 (O4443_07965) 1697517..1697840 + 324 WP_042462902.1 hypothetical protein -
O4443_RS07970 (O4443_07970) 1697837..1698358 + 522 WP_010893241.1 hypothetical protein -
O4443_RS07975 (O4443_07975) 1698334..1698876 + 543 WP_023907873.1 hypothetical protein -
O4443_RS07980 (O4443_07980) 1698873..1699460 + 588 WP_031336754.1 phage baseplate assembly protein V -
O4443_RS07985 (O4443_07985) 1699506..1699787 - 282 WP_060872142.1 type II toxin-antitoxin system YafQ family toxin Toxin
O4443_RS07990 (O4443_07990) 1699774..1700037 - 264 WP_060872141.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
O4443_RS07995 (O4443_07995) 1700202..1700525 + 324 WP_282454360.1 GPW/gp25 family protein -
O4443_RS08000 (O4443_08000) 1700525..1701418 + 894 WP_282454361.1 baseplate J/gp47 family protein -
O4443_RS08005 (O4443_08005) 1701411..1701968 + 558 WP_031336758.1 phage tail protein I -
O4443_RS08010 (O4443_08010) 1701976..1703568 + 1593 WP_282454362.1 hypothetical protein -
O4443_RS08015 (O4443_08015) 1703633..1704811 + 1179 WP_282454363.1 phage tail sheath family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1668636..1713653 45017


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(1-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-84)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10873.32 Da        Isoelectric Point: 7.5805

>T266718 WP_060872142.1 NZ_CP114551:c1699787-1699506 [Xylella fastidiosa subsp. pauca]
MRRISQTGQFKRDYKREAKGQHRATLDEELIHVVHALACDHPLEPRHHDHALTGSWKDHRDCHIKPDLVLIYRKPDDETL
QLVRIGSHSELGL

Download         Length: 282 bp

Antitoxin


Download         Length: 88 a.a.        Molecular weight: 9437.91 Da        Isoelectric Point: 6.2180

>AT266718 WP_060872141.1 NZ_CP114551:c1700037-1699774 [Xylella fastidiosa subsp. pauca]
MSANAVVRARVDAHIKEEASTVLATMGLSVSDAFRMMLTRIAREKALPFEPLVPNATTIAAMREARAGHLKSFDSIEALM
ADLHAED

Download         Length: 264 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1L2ALG3

Antitoxin

Source ID Structure
AlphaFold DB A0A1L2ALQ3

References