Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relB-parE/ParE-RHH |
Location | 1410510..1411072 | Replicon | chromosome |
Accession | NZ_CP114550 | ||
Organism | Xylella fastidiosa subsp. pauca strain AM2-Angelina |
Toxin (Protein)
Gene name | parE | Uniprot ID | Q9PBR6 |
Locus tag | O4445_RS06670 | Protein ID | WP_010894527.1 |
Coordinates | 1410510..1410806 (-) | Length | 99 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q9PBR5 |
Locus tag | O4445_RS06675 | Protein ID | WP_010894528.1 |
Coordinates | 1410794..1411072 (-) | Length | 93 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
O4445_RS06615 (O4445_06615) | 1405588..1405797 | + | 210 | WP_010894516.1 | hypothetical protein | - |
O4445_RS06620 (O4445_06620) | 1405827..1406362 | - | 536 | Protein_1292 | recombinase family protein | - |
O4445_RS06625 (O4445_06625) | 1406356..1406595 | - | 240 | WP_069107122.1 | hypothetical protein | - |
O4445_RS06630 (O4445_06630) | 1406611..1406880 | - | 270 | WP_010894518.1 | hypothetical protein | - |
O4445_RS06635 (O4445_06635) | 1406989..1407297 | - | 309 | WP_010894519.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
O4445_RS06640 (O4445_06640) | 1407301..1407573 | - | 273 | WP_010894520.1 | hypothetical protein | - |
O4445_RS06645 (O4445_06645) | 1407570..1408025 | - | 456 | WP_010894521.1 | hypothetical protein | - |
O4445_RS06650 (O4445_06650) | 1408434..1408523 | - | 90 | WP_228762876.1 | hypothetical protein | - |
O4445_RS06655 (O4445_06655) | 1408605..1408868 | - | 264 | WP_023906433.1 | hypothetical protein | - |
O4445_RS06660 (O4445_06660) | 1409433..1409618 | - | 186 | WP_010894523.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
O4445_RS06665 (O4445_06665) | 1409611..1409853 | - | 243 | WP_010894524.1 | type II toxin-antitoxin system ParD family antitoxin | - |
O4445_RS06670 (O4445_06670) | 1410510..1410806 | - | 297 | WP_010894527.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
O4445_RS06675 (O4445_06675) | 1410794..1411072 | - | 279 | WP_010894528.1 | CopG family ribbon-helix-helix protein | Antitoxin |
O4445_RS06680 (O4445_06680) | 1411855..1412514 | + | 660 | WP_010894530.1 | hypothetical protein | - |
O4445_RS06685 (O4445_06685) | 1412534..1412896 | + | 363 | WP_143704175.1 | hypothetical protein | - |
O4445_RS06690 (O4445_06690) | 1413007..1413261 | + | 255 | Protein_1306 | conjugal transfer protein TrbJ | - |
O4445_RS06695 (O4445_06695) | 1413314..1413595 | - | 282 | WP_010894533.1 | type II toxin-antitoxin system YafQ family toxin | - |
O4445_RS06700 (O4445_06700) | 1413582..1413842 | - | 261 | WP_010894534.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | - |
O4445_RS06705 (O4445_06705) | 1414172..1414978 | - | 807 | WP_010894535.1 | oxidoreductase | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 99 a.a. Molecular weight: 11155.72 Da Isoelectric Point: 7.4670
>T266703 WP_010894527.1 NZ_CP114550:c1410806-1410510 [Xylella fastidiosa subsp. pauca]
MPRVIFAPEAILNIQRLRNFLHPKNTDAARRAGEAIMRGARMLGAQPHIGRPVDDMPDEYREWLIDFGDSGYVARYHIDG
DTVTILAVRHHKEVGYTS
MPRVIFAPEAILNIQRLRNFLHPKNTDAARRAGEAIMRGARMLGAQPHIGRPVDDMPDEYREWLIDFGDSGYVARYHIDG
DTVTILAVRHHKEVGYTS
Download Length: 297 bp
Antitoxin
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S0VAK4 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A1S0V821 |