Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-dinJ/YafQ-RelB
Location 994583..995111 Replicon chromosome
Accession NZ_CP114549
Organism Xylella fastidiosa subsp. pauca strain ALM4

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O4444_RS04270 Protein ID WP_010894533.1
Coordinates 994830..995111 (+) Length 94 a.a.

Antitoxin (Protein)


Gene name dinJ Uniprot ID Q9PBQ9
Locus tag O4444_RS04265 Protein ID WP_010894534.1
Coordinates 994583..994843 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O4444_RS04255 (O4444_04255) 990339..993401 + 3063 WP_010894536.1 efflux RND transporter permease subunit -
O4444_RS04260 (O4444_04260) 993447..994253 + 807 WP_010894535.1 oxidoreductase -
O4444_RS04265 (O4444_04265) 994583..994843 + 261 WP_010894534.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
O4444_RS04270 (O4444_04270) 994830..995111 + 282 WP_010894533.1 type II toxin-antitoxin system YafQ family toxin Toxin
O4444_RS04275 (O4444_04275) 995164..995418 - 255 Protein_827 conjugal transfer protein TrbJ -
O4444_RS04280 (O4444_04280) 995529..995891 - 363 WP_143704175.1 hypothetical protein -
O4444_RS04285 (O4444_04285) 995911..996570 - 660 WP_010894530.1 hypothetical protein -
O4444_RS04290 (O4444_04290) 997353..997631 + 279 WP_010894528.1 CopG family ribbon-helix-helix protein -
O4444_RS04295 (O4444_04295) 997619..997915 + 297 WP_010894527.1 type II toxin-antitoxin system RelE/ParE family toxin -
O4444_RS04300 (O4444_04300) 998572..998814 + 243 WP_010894524.1 type II toxin-antitoxin system ParD family antitoxin -
O4444_RS04305 (O4444_04305) 998807..998992 + 186 WP_010894523.1 type II toxin-antitoxin system RelE/ParE family toxin -
O4444_RS04310 (O4444_04310) 999250..999507 + 258 WP_140190226.1 hypothetical protein -
O4444_RS04315 (O4444_04315) 999557..999820 + 264 WP_023906433.1 hypothetical protein -
O4444_RS04320 (O4444_04320) 999902..999991 + 90 WP_228762876.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, YafQ-like toxin

(2-91)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-68)


Sequences

Toxin        


Download         Length: 94 a.a.        Molecular weight: 10727.49 Da        Isoelectric Point: 9.0869

>T266687 WP_010894533.1 NZ_CP114549:994830-995111 [Xylella fastidiosa subsp. pauca]
VREIKQLGQFKRDLKREAKGQHRATLEDDLLPVIDALAKDMPLEPRHRDHALLGNWKDLRDCHIKLDLVLIYTRVDSKTL
TLVRLGSHAELGL

Download         Length: 282 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 8997.58 Da        Isoelectric Point: 10.5972

>AT266687 WP_010894534.1 NZ_CP114549:994583-994843 [Xylella fastidiosa subsp. pauca]
MAANQLVQARIDGAIKAEATVVLAAMGLTISDAVRLLLTKVAQDKALPFEPLIPNATTIKAMREARAGKGETVTLGELRA
TIRAGN

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB Q9PBQ9

References