Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 27861..28371 Replicon plasmid unnamed5
Accession NZ_CP114548
Organism Ligilactobacillus salivarius strain S92

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U06_RS11390 Protein ID WP_044006010.1
Coordinates 27861..28112 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U06_RS11395 Protein ID WP_044006009.1
Coordinates 28105..28371 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U06_RS11360 23189..23323 - 135 WP_283475131.1 hypothetical protein -
O2U06_RS11365 23527..24039 - 513 WP_283548122.1 hypothetical protein -
O2U06_RS11370 24481..24879 - 399 WP_087250758.1 hypothetical protein -
O2U06_RS11375 24888..25985 - 1098 WP_044006012.1 ParM/StbA family protein -
O2U06_RS11380 26300..26617 + 318 WP_283548105.1 hypothetical protein -
O2U06_RS11385 26797..27405 + 609 WP_283548106.1 hypothetical protein -
O2U06_RS11390 27861..28112 - 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U06_RS11395 28105..28371 - 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U06_RS11400 28466..28801 - 336 WP_283475111.1 hypothetical protein -
O2U06_RS11405 29721..30056 - 336 WP_283475113.1 hypothetical protein -
O2U06_RS11410 30203..30589 - 387 WP_283475114.1 hypothetical protein -
O2U06_RS11415 30693..31106 - 414 WP_283475116.1 hypothetical protein -
O2U06_RS11420 31227..32459 - 1233 WP_283475118.1 RepB family plasmid replication initiator protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..47535 47535


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266686 WP_044006010.1 NZ_CP114548:c28112-27861 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266686 WP_044006009.1 NZ_CP114548:c28371-28105 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References