Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 28749..29259 Replicon plasmid unnamed3
Accession NZ_CP114546
Organism Ligilactobacillus salivarius strain S92

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U06_RS10905 Protein ID WP_044006010.1
Coordinates 29008..29259 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U06_RS10900 Protein ID WP_044006009.1
Coordinates 28749..29015 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U06_RS10870 24663..25838 + 1176 WP_283548093.1 RepB family plasmid replication initiator protein -
O2U06_RS10875 26015..26428 + 414 WP_283475116.1 hypothetical protein -
O2U06_RS10880 26532..26918 + 387 WP_283475114.1 hypothetical protein -
O2U06_RS10885 27065..27400 + 336 WP_283475113.1 hypothetical protein -
O2U06_RS10890 27531..27830 + 300 WP_283548094.1 hypothetical protein -
O2U06_RS10895 28319..28654 + 336 WP_283475111.1 hypothetical protein -
O2U06_RS10900 28749..29015 + 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U06_RS10905 29008..29259 + 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U06_RS10910 29715..30821 - 1107 WP_283475109.1 hypothetical protein -
O2U06_RS10915 31137..31334 + 198 WP_283548095.1 hypothetical protein -
O2U06_RS10920 31364..32233 + 870 WP_283548096.1 ParM/StbA family protein -
O2U06_RS10925 32242..32640 + 399 WP_087250758.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..33883 33883


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266685 WP_044006010.1 NZ_CP114546:29008-29259 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266685 WP_044006009.1 NZ_CP114546:28749-29015 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References