266684

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/LOTUS_5_Limkain_b1-RHH
Location 2966210..2966784 Replicon chromosome
Accession NZ_CP114542
Organism Brevundimonas subvibrioides strain Br6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O3139_RS14675 Protein ID WP_269514836.1
Coordinates 2966210..2966575 (-) Length 122 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O3139_RS14680 Protein ID WP_269514837.1
Coordinates 2966569..2966784 (-) Length 72 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3139_RS14655 2961990..2962397 - 408 WP_269514833.1 GxxExxY protein -
O3139_RS14660 2962434..2963609 - 1176 WP_269516501.1 aspartate aminotransferase family protein -
O3139_RS14665 2963859..2964680 - 822 WP_269514834.1 ABC transporter permease -
O3139_RS14670 2964800..2966197 - 1398 WP_269514835.1 dihydrolipoyl dehydrogenase -
O3139_RS14675 2966210..2966575 - 366 WP_269514836.1 type II toxin-antitoxin system VapC family toxin Toxin
O3139_RS14680 2966569..2966784 - 216 WP_269514837.1 ribbon-helix-helix protein, CopG family Antitoxin
O3139_RS14685 2966845..2968623 - 1779 WP_269514838.1 2-oxo acid dehydrogenase subunit E2 -
O3139_RS14690 2968623..2969744 - 1122 WP_269514839.1 alpha-ketoacid dehydrogenase subunit beta -
O3139_RS14695 2969741..2970973 - 1233 WP_269514840.1 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) subunit alpha -
O3139_RS14700 2971118..2971609 + 492 WP_209321921.1 Lrp/AsnC family transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(5-106)

Antitoxin

Ribbon-helix-helix protein, CopG

(7-40)


Sequences

Toxin        


Download         Length: 122 a.a.        Molecular weight: 13386.18 Da        Isoelectric Point: 4.3367

>T266684 WP_269514836.1 NZ_CP114542:c2966575-2966210 [Brevundimonas subvibrioides]
MVKALFDTNILIDHLNAAPEADAEIDRYDDRAISIITWIEVMAGADAELADPTRTYLDGYSIVALDDPIAERAASIRQSR
RMKLPDAIIWATAQTTGRLLVTRNTKDFPADDPGVRAPYVL

Download         Length: 366 bp

Antitoxin


Download         Length: 72 a.a.        Molecular weight: 8013.05 Da        Isoelectric Point: 8.5613

>AT266684 WP_269514837.1 NZ_CP114542:c2966784-2966569 [Brevundimonas subvibrioides]
MRILVDANEEQVAALDALAKREKRPRAAVIRAAIDDYVARNKRQAVKDGFGLWGQGGEDGLAYQERLRSEW

Download         Length: 216 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References