266683

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/upstrm_HI1419-dnstrm_HI1420
Location 2880629..2881253 Replicon chromosome
Accession NZ_CP114542
Organism Brevundimonas subvibrioides strain Br6

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O3139_RS14255 Protein ID WP_269514762.1
Coordinates 2880927..2881253 (-) Length 109 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag O3139_RS14250 Protein ID WP_269514761.1
Coordinates 2880629..2880937 (-) Length 103 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3139_RS14230 2877100..2877519 - 420 WP_269514758.1 large-conductance mechanosensitive channel protein MscL -
O3139_RS14235 2877537..2877827 - 291 WP_209322409.1 integration host factor subunit beta -
O3139_RS14240 2878121..2879824 - 1704 WP_269514759.1 30S ribosomal protein S1 -
O3139_RS14245 2879982..2880632 - 651 WP_269514760.1 (d)CMP kinase -
O3139_RS14250 2880629..2880937 - 309 WP_269514761.1 putative addiction module antidote protein Antitoxin
O3139_RS14255 2880927..2881253 - 327 WP_269514762.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
O3139_RS14260 2881258..2882556 - 1299 WP_269516498.1 3-phosphoshikimate 1-carboxyvinyltransferase -
O3139_RS14265 2882712..2883176 + 465 WP_209322405.1 TIGR02300 family protein -
O3139_RS14275 2883481..2885175 - 1695 WP_269514763.1 MFS transporter -
O3139_RS14280 2885346..2885759 + 414 WP_269514764.1 Hsp20 family protein -
O3139_RS14285 2885850..2886104 + 255 WP_269516499.1 DUF1150 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Addiction module killer protein, predicted

(15-104)

Antitoxin

Uncharacterized protein HI1420

(7-94)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 12155.59 Da        Isoelectric Point: 7.2042

>T266683 WP_269514762.1 NZ_CP114542:c2881253-2880927 [Brevundimonas subvibrioides]
MSPIDDSSGFELEFSETFDAWLQGLRDHRAAARITVRLERLERGHWGDARSVGEGVTELRIDYGPGYRLYAARRGRRIVL
MLAGGDKSSQRRDIEAAKVLAREYGDGT

Download         Length: 327 bp

Antitoxin


Download         Length: 103 a.a.        Molecular weight: 10998.75 Da        Isoelectric Point: 4.8409

>AT266683 WP_269514761.1 NZ_CP114542:c2880937-2880629 [Brevundimonas subvibrioides]
MAPDTIPFDPARYLNAPEAIEEYLVASFEEAAEYGDPGIITKALGTVARAKGMTKMAEDAELSRTALYRALSAEGRPELA
TIFKVMQALGLRLAPVRMKPAA

Download         Length: 309 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References