Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 2279701..2280341 Replicon chromosome
Accession NZ_CP114542
Organism Brevundimonas subvibrioides strain Br6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O3139_RS11440 Protein ID WP_269514198.1
Coordinates 2279701..2280090 (-) Length 130 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O3139_RS11445 Protein ID WP_269514199.1
Coordinates 2280087..2280341 (-) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3139_RS11425 2275266..2276228 - 963 WP_269514195.1 M20/M25/M40 family metallo-hydrolase -
O3139_RS11430 2276341..2278656 + 2316 WP_269514196.1 NAD-dependent DNA ligase LigA -
O3139_RS11435 2278653..2279642 - 990 WP_269514197.1 aldo/keto reductase -
O3139_RS11440 2279701..2280090 - 390 WP_269514198.1 type II toxin-antitoxin system VapC family toxin Toxin
O3139_RS11445 2280087..2280341 - 255 WP_269514199.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
O3139_RS11450 2280376..2282187 - 1812 WP_269514200.1 aminopeptidase P family protein -
O3139_RS11455 2282205..2283074 - 870 WP_269514201.1 50S ribosomal protein L11 methyltransferase -
O3139_RS11460 2283176..2283766 + 591 WP_269514202.1 hypothetical protein -
O3139_RS11465 2283840..2284052 - 213 WP_269514203.1 DUF3126 family protein -
O3139_RS11470 2284124..2284945 - 822 WP_269514204.1 serine O-acetyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-125)

Antitoxin

Antitoxin VapB-like

(2-83)


Sequences

Toxin        


Download         Length: 130 a.a.        Molecular weight: 14701.80 Da        Isoelectric Point: 5.2866

>T266681 WP_269514198.1 NZ_CP114542:c2280090-2279701 [Brevundimonas subvibrioides]
MIVDSSALVAILFNEPEAAEFARLMMREPCRISAANYFEAGMVVDRKTRDEIPRQAFDTLVATTRLDIVDVTREQADEAR
MAYRRFGKGYHEARLNFGDCFAYVLARRTGEPLLFKGDDFARTDVVRAL

Download         Length: 390 bp

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9214.44 Da        Isoelectric Point: 4.4607

>AT266681 WP_269514199.1 NZ_CP114542:c2280341-2280087 [Brevundimonas subvibrioides]
MLNIKNPETHRLARELAARRGESLTTAVTVALREQLAREPVEPPSATVEDIMALVRSIQPHLTPLEPGEDPTAFLYDDET
GLPG

Download         Length: 255 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References