Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC-VagC
Location 993054..993703 Replicon chromosome
Accession NZ_CP114542
Organism Brevundimonas subvibrioides strain Br6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O3139_RS04960 Protein ID WP_269515869.1
Coordinates 993299..993703 (+) Length 135 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O3139_RS04955 Protein ID WP_269515868.1
Coordinates 993054..993302 (+) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3139_RS04935 988501..989457 + 957 WP_269515864.1 hypothetical protein -
O3139_RS04940 989465..989731 - 267 WP_269515865.1 hypothetical protein -
O3139_RS04945 989920..991068 - 1149 WP_269515866.1 patatin-like phospholipase family protein -
O3139_RS04950 991161..993029 + 1869 WP_269515867.1 DNA primase -
O3139_RS04955 993054..993302 + 249 WP_269515868.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
O3139_RS04960 993299..993703 + 405 WP_269515869.1 type II toxin-antitoxin system VapC family toxin Toxin
O3139_RS04965 993700..994038 + 339 WP_269515870.1 hypothetical protein -
O3139_RS04970 994131..996095 + 1965 WP_269515871.1 RNA polymerase sigma factor RpoD -
O3139_RS04975 996136..996486 - 351 WP_269515872.1 DUF1428 domain-containing protein -
O3139_RS04980 996525..996734 - 210 WP_269515873.1 flagellar hook protein FlgE -
O3139_RS04985 996731..998407 - 1677 WP_269515874.1 pilus assembly protein TadG-related protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(4-124)

Antitoxin

SpoVT-AbrB domain

(15-49)


Sequences

Toxin        


Download         Length: 135 a.a.        Molecular weight: 14437.58 Da        Isoelectric Point: 7.1679

>T266678 WP_269515869.1 NZ_CP114542:993299-993703 [Brevundimonas subvibrioides]
MIRYLLDTNMLSDLVRRPLGGVRQRVALVGEAAVGTSIVVAAEARFGAARASSARLTDQLERILSELVVLPFEAPADRHY
ADVRSALTRAGTPIGANDTLIAAHALALNCILVTDNEREFGRVSGLSIENWLRA

Download         Length: 405 bp

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9417.77 Da        Isoelectric Point: 4.4076

>AT266678 WP_269515868.1 NZ_CP114542:993054-993302 [Brevundimonas subvibrioides]
MLVRAVQNSRSVKLFRNGRNQAVRIPREFELPGEDAVMRREGDRLIIELPERIGLLALLSTLDPIDEDFALIEDARPEDV
DF

Download         Length: 249 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References