Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/PIN(toxin)
Location 869286..869947 Replicon chromosome
Accession NZ_CP114542
Organism Brevundimonas subvibrioides strain Br6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O3139_RS04295 Protein ID WP_269515729.1
Coordinates 869286..869726 (-) Length 147 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O3139_RS04300 Protein ID WP_269515730.1
Coordinates 869723..869947 (-) Length 75 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3139_RS04255 864551..865225 - 675 WP_269515715.1 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase -
O3139_RS04260 865304..865522 - 219 WP_269515718.1 hypothetical protein -
O3139_RS04265 865522..866115 - 594 WP_269515719.1 peptide deformylase -
O3139_RS04270 866214..866660 + 447 WP_269515721.1 tol-pal system-associated acyl-CoA thioesterase -
O3139_RS04275 866749..867159 + 411 WP_269515723.1 hypothetical protein -
O3139_RS04280 867253..868017 + 765 WP_269515725.1 protein TolQ -
O3139_RS04285 868019..868471 + 453 WP_269515727.1 ExbD/TolR family protein -
O3139_RS04290 868474..869289 + 816 WP_269515728.1 hypothetical protein -
O3139_RS04295 869286..869726 - 441 WP_269515729.1 PIN domain-containing protein Toxin
O3139_RS04300 869723..869947 - 225 WP_269515730.1 CopG family transcriptional regulator Antitoxin
O3139_RS04305 870122..871522 + 1401 WP_269515731.1 Tol-Pal system beta propeller repeat protein TolB -
O3139_RS04310 871606..872160 + 555 WP_269515732.1 peptidoglycan-associated lipoprotein Pal -
O3139_RS04315 872269..873375 + 1107 WP_269515733.1 DUF3667 domain-containing protein -
O3139_RS04320 873421..874278 + 858 WP_269515734.1 tol-pal system protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(3-127)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 147 a.a.        Molecular weight: 15908.30 Da        Isoelectric Point: 6.7489

>T266677 WP_269515729.1 NZ_CP114542:c869726-869286 [Brevundimonas subvibrioides]
MIYLLDANVLIALIDPDHVHSDYAKAWFERTIDEGWATCPITQHAFIRIAGKPSYQMPGTAAAMAEILGRVCQRPGHVFW
PETISLLTSPLVDPARLTSHGQVTDTYLLALAVHNGGKLATFDRRLSTRAVKGGDAALEIIGTLTN

Download         Length: 441 bp

Antitoxin


Download         Length: 75 a.a.        Molecular weight: 8360.33 Da        Isoelectric Point: 4.4230

>AT266677 WP_269515730.1 NZ_CP114542:c869947-869723 [Brevundimonas subvibrioides]
MRTTLTIDDDLLERARAIADYENRSIGEVVSERLRKSFEAPASSTDMWNGFPQLPRRGAVVTMAMVNASRDEED

Download         Length: 225 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References