Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/DUF433(antitoxin)
Location 860085..860635 Replicon chromosome
Accession NZ_CP114542
Organism Brevundimonas subvibrioides strain Br6

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O3139_RS04220 Protein ID WP_269515705.1
Coordinates 860309..860635 (+) Length 109 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O3139_RS04215 Protein ID WP_269515704.1
Coordinates 860085..860312 (+) Length 76 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3139_RS04205 856695..857843 - 1149 WP_269515701.1 efflux RND transporter periplasmic adaptor subunit -
O3139_RS04210 858069..859877 + 1809 WP_269515702.1 translation elongation factor 4 -
O3139_RS04215 860085..860312 + 228 WP_269515704.1 DUF433 domain-containing protein Antitoxin
O3139_RS04220 860309..860635 + 327 WP_269515705.1 DUF5615 family PIN-like protein Toxin
O3139_RS04225 860632..860845 + 214 Protein_836 elongation factor 4 -
O3139_RS04230 860847..861566 + 720 WP_269515707.1 SseB family protein -
O3139_RS04235 861926..862132 + 207 WP_269515708.1 hypothetical protein -
O3139_RS04240 862142..863134 + 993 WP_269515710.1 HNH endonuclease signature motif containing protein -
O3139_RS04245 863357..863602 + 246 WP_269515712.1 hypothetical protein -
O3139_RS04250 863813..864592 + 780 WP_269515714.1 hypothetical protein -
O3139_RS04255 864551..865225 - 675 WP_269515715.1 bifunctional 4-hydroxy-2-oxoglutarate aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase -
O3139_RS04260 865304..865522 - 219 WP_269515718.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Domain of unknown function DUF5615

(2-75)

Antitoxin

Protein of unknown function DUF433

(8-63)


Sequences

Toxin        


Download         Length: 109 a.a.        Molecular weight: 11884.57 Da        Isoelectric Point: 4.8362

>T266676 WP_269515705.1 NZ_CP114542:860309-860635 [Brevundimonas subvibrioides]
VRIVVDQQLPPLLADWFRDQGIAAIHVRDLGMSAAPDAAIWAEAARDDAVVLSRDEDFVGLTRAGSARLVWIRIGNCANA
TLLAAVEANWPAIRRRLEDGERLVELRS

Download         Length: 327 bp

Antitoxin


Download         Length: 76 a.a.        Molecular weight: 8037.31 Da        Isoelectric Point: 4.6815

>AT266676 WP_269515704.1 NZ_CP114542:860085-860312 [Brevundimonas subvibrioides]
MSELLARITIRPDTCGGRPCIRGMRIRVSDVLGMLAAGETPASILEYHPDLEAEDISACLAYAAREVDHAVILAA

Download         Length: 228 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References