266674

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) hicAB/-
Location 506993..507603 Replicon chromosome
Accession NZ_CP114542
Organism Brevundimonas subvibrioides strain Br6

Toxin (Protein)


Gene name hicA Uniprot ID -
Locus tag O3139_RS02550 Protein ID WP_269515338.1
Coordinates 507337..507603 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name hicB Uniprot ID -
Locus tag O3139_RS02545 Protein ID WP_269515337.1
Coordinates 506993..507340 (-) Length 116 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3139_RS02515 502084..502905 + 822 WP_209322280.1 enoyl-ACP reductase -
O3139_RS02520 503334..503507 + 174 WP_209322281.1 DUF1508 domain-containing protein -
O3139_RS02525 503504..504025 - 522 WP_269515333.1 ribosome maturation factor RimM -
O3139_RS02530 504210..504809 - 600 WP_269515334.1 30S ribosomal protein S16 -
O3139_RS02535 504831..506381 - 1551 WP_269515335.1 signal recognition particle protein -
O3139_RS02540 506653..506808 + 156 WP_269515336.1 hypothetical protein -
O3139_RS02545 506993..507340 - 348 WP_269515337.1 type II toxin-antitoxin system HicB family antitoxin Antitoxin
O3139_RS02550 507337..507603 - 267 WP_269515338.1 type II toxin-antitoxin system HicA family toxin Toxin
O3139_RS02555 507713..510421 + 2709 WP_269515339.1 phosphoenolpyruvate carboxylase -
O3139_RS02560 510418..511020 - 603 WP_269515340.1 recombination mediator RecR -
O3139_RS02565 511022..511351 - 330 WP_269515341.1 YbaB/EbfC family nucleoid-associated protein -
O3139_RS02570 511490..512101 + 612 WP_269515342.1 malonic semialdehyde reductase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

HicA mRNA interferase family

(23-80)

Antitoxin

Uncharacterised protein family HicB

(54-104)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 9473.70 Da        Isoelectric Point: 11.0117

>T266674 WP_269515338.1 NZ_CP114542:c507603-507337 [Brevundimonas subvibrioides]
VKGKHARTLDAIFADPVRANVAWSDVEALFSAAGGTISEGRGSRVRVSLNAVDAVFHRPHPQKETDKGALKSVRRFLTEA
GHAPDAKR

Download         Length: 267 bp

Antitoxin


Download         Length: 116 a.a.        Molecular weight: 12579.10 Da        Isoelectric Point: 5.6004

>AT266674 WP_269515337.1 NZ_CP114542:c507340-506993 [Brevundimonas subvibrioides]
MTTMTHDGYLATVELDEAAGLFHGEVINTRDVLTFQGRTPDELKTAFADTIADYLDWCRERGKTPDKPFSGTFSVRVAPE
VHRRAAAAAAREGKSLNGFVAELLDRASLGKHEAV

Download         Length: 348 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References