Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 132779..133289 Replicon plasmid unnamed2
Accession NZ_CP114523
Organism Ligilactobacillus salivarius strain S96

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U07_RS01835 Protein ID WP_044006010.1
Coordinates 132779..133030 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U07_RS01840 Protein ID WP_044006009.1
Coordinates 133023..133289 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U07_RS01810 (O2U07_01810) 128110..128259 - 150 WP_283475507.1 hypothetical protein -
O2U07_RS01815 (O2U07_01815) 128270..128878 - 609 WP_283475520.1 hypothetical protein -
O2U07_RS01820 (O2U07_01820) 129400..129642 - 243 WP_283475504.1 hypothetical protein -
O2U07_RS01825 (O2U07_01825) 129806..130903 - 1098 WP_044006012.1 ParM/StbA family protein -
O2U07_RS01830 (O2U07_01830) 131217..132323 + 1107 WP_283475109.1 hypothetical protein -
O2U07_RS01835 (O2U07_01835) 132779..133030 - 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U07_RS01840 (O2U07_01840) 133023..133289 - 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U07_RS01845 (O2U07_01845) 133384..133719 - 336 WP_283475111.1 hypothetical protein -
O2U07_RS01850 (O2U07_01850) 134207..134488 - 282 WP_094372154.1 hypothetical protein -
O2U07_RS01855 (O2U07_01855) 134638..134973 - 336 WP_283475113.1 hypothetical protein -
O2U07_RS01860 (O2U07_01860) 135120..135479 - 360 WP_283475502.1 hypothetical protein -
O2U07_RS01865 (O2U07_01865) 135610..136023 - 414 WP_283475116.1 hypothetical protein -
O2U07_RS01870 (O2U07_01870) 136144..137331 - 1188 WP_283475500.1 RepB family plasmid replication initiator protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..144910 144910


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266673 WP_044006010.1 NZ_CP114523:c133030-132779 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266673 WP_044006009.1 NZ_CP114523:c133289-133023 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References