Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 117691..118201 Replicon plasmid unnamed2
Accession NZ_CP114523
Organism Ligilactobacillus salivarius strain S96

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U07_RS01745 Protein ID WP_044006010.1
Coordinates 117950..118201 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U07_RS01740 Protein ID WP_044006009.1
Coordinates 117691..117957 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U07_RS01710 (O2U07_01710) 113650..114837 + 1188 WP_283475500.1 RepB family plasmid replication initiator protein -
O2U07_RS01715 (O2U07_01715) 114958..115371 + 414 WP_283475116.1 hypothetical protein -
O2U07_RS01720 (O2U07_01720) 115502..115861 + 360 WP_283475502.1 hypothetical protein -
O2U07_RS01725 (O2U07_01725) 116007..116342 + 336 WP_283475113.1 hypothetical protein -
O2U07_RS01730 (O2U07_01730) 116492..116773 + 282 WP_094372154.1 hypothetical protein -
O2U07_RS01735 (O2U07_01735) 117261..117596 + 336 WP_283475111.1 hypothetical protein -
O2U07_RS01740 (O2U07_01740) 117691..117957 + 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U07_RS01745 (O2U07_01745) 117950..118201 + 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U07_RS01750 (O2U07_01750) 118657..119763 - 1107 WP_283475109.1 hypothetical protein -
O2U07_RS01755 (O2U07_01755) 120078..121175 + 1098 WP_044006012.1 ParM/StbA family protein -
O2U07_RS01760 (O2U07_01760) 121339..121581 + 243 WP_283475504.1 hypothetical protein -
O2U07_RS01765 (O2U07_01765) 122099..122698 + 600 WP_283475506.1 hypothetical protein -
O2U07_RS01770 (O2U07_01770) 122719..122868 + 150 WP_283475507.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..144910 144910


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266672 WP_044006010.1 NZ_CP114523:117950-118201 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266672 WP_044006009.1 NZ_CP114523:117691-117957 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References