Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 6126..6636 Replicon plasmid unnamed2
Accession NZ_CP114523
Organism Ligilactobacillus salivarius strain S96

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U07_RS01115 Protein ID WP_044006010.1
Coordinates 6126..6377 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U07_RS01120 Protein ID WP_044006009.1
Coordinates 6370..6636 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U07_RS01095 (O2U07_01095) 1448..2299 - 852 WP_283475147.1 hypothetical protein -
O2U07_RS01100 (O2U07_01100) 2745..3143 - 399 WP_087250758.1 hypothetical protein -
O2U07_RS01105 (O2U07_01105) 3152..4249 - 1098 WP_044006012.1 ParM/StbA family protein -
O2U07_RS01110 (O2U07_01110) 4564..5670 + 1107 WP_283475109.1 hypothetical protein -
O2U07_RS01115 (O2U07_01115) 6126..6377 - 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U07_RS01120 (O2U07_01120) 6370..6636 - 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U07_RS01125 (O2U07_01125) 6731..7066 - 336 WP_283475111.1 hypothetical protein -
O2U07_RS01130 (O2U07_01130) 7555..7836 - 282 WP_094372154.1 hypothetical protein -
O2U07_RS01135 (O2U07_01135) 7986..8321 - 336 WP_283475113.1 hypothetical protein -
O2U07_RS01140 (O2U07_01140) 8468..8827 - 360 WP_283475502.1 hypothetical protein -
O2U07_RS01145 (O2U07_01145) 8958..9371 - 414 WP_283475116.1 hypothetical protein -
O2U07_RS01150 (O2U07_01150) 9492..10724 - 1233 WP_283475118.1 RepB family plasmid replication initiator protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..144910 144910


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266671 WP_044006010.1 NZ_CP114523:c6377-6126 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266671 WP_044006009.1 NZ_CP114523:c6636-6370 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References