Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 131904..132414 Replicon plasmid unnamed1
Accession NZ_CP114518
Organism Ligilactobacillus salivarius strain S91

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U05_RS00770 Protein ID WP_044006010.1
Coordinates 131904..132155 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U05_RS00775 Protein ID WP_044006009.1
Coordinates 132148..132414 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U05_RS00740 (O2U05_00735) 127231..127383 - 153 WP_283558373.1 hypothetical protein -
O2U05_RS00745 (O2U05_00740) 127404..128081 - 678 WP_283558374.1 hypothetical protein -
O2U05_RS00750 (O2U05_00745) 128639..128923 - 285 WP_283558370.1 hypothetical protein -
O2U05_RS00755 (O2U05_00750) 128932..130029 - 1098 WP_044006012.1 ParM/StbA family protein -
O2U05_RS00760 (O2U05_00755) 130343..130660 + 318 WP_283548105.1 hypothetical protein -
O2U05_RS00765 (O2U05_00760) 130840..131448 + 609 WP_283548106.1 hypothetical protein -
O2U05_RS00770 (O2U05_00765) 131904..132155 - 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U05_RS00775 (O2U05_00770) 132148..132414 - 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U05_RS00780 (O2U05_00775) 133762..134097 - 336 WP_283475113.1 hypothetical protein -
O2U05_RS00785 (O2U05_00780) 134244..134630 - 387 WP_283475114.1 hypothetical protein -
O2U05_RS00790 (O2U05_00785) 134734..135147 - 414 WP_283475116.1 hypothetical protein -
O2U05_RS00795 (O2U05_00790) 135268..135666 - 399 WP_283558379.1 hypothetical protein -
O2U05_RS00800 (O2U05_00795) 135708..136499 - 792 WP_283558368.1 replication initiation protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..144347 144347


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266670 WP_044006010.1 NZ_CP114518:c132155-131904 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266670 WP_044006009.1 NZ_CP114518:c132414-132148 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References