Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 116794..117304 Replicon plasmid unnamed1
Accession NZ_CP114518
Organism Ligilactobacillus salivarius strain S91

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U05_RS00675 Protein ID WP_044006010.1
Coordinates 117053..117304 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U05_RS00670 Protein ID WP_044006009.1
Coordinates 116794..117060 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U05_RS00645 (O2U05_00640) 112708..113499 + 792 WP_283558368.1 replication initiation protein -
O2U05_RS00650 (O2U05_00645) 113541..113939 + 399 WP_283558379.1 hypothetical protein -
O2U05_RS00655 (O2U05_00650) 114060..114473 + 414 WP_283475116.1 hypothetical protein -
O2U05_RS00660 (O2U05_00655) 114577..114963 + 387 WP_283475114.1 hypothetical protein -
O2U05_RS00665 (O2U05_00660) 115110..115445 + 336 WP_283475113.1 hypothetical protein -
O2U05_RS00670 (O2U05_00665) 116794..117060 + 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U05_RS00675 (O2U05_00670) 117053..117304 + 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U05_RS00680 (O2U05_00675) 117959..118366 - 408 WP_283558369.1 hypothetical protein -
O2U05_RS00685 (O2U05_00680) 118546..118863 - 318 WP_283548105.1 hypothetical protein -
O2U05_RS00690 (O2U05_00685) 119177..120274 + 1098 WP_044006012.1 ParM/StbA family protein -
O2U05_RS00695 (O2U05_00690) 120283..120567 + 285 WP_283558370.1 hypothetical protein -
O2U05_RS00700 (O2U05_00695) 121126..121977 + 852 WP_283475147.1 hypothetical protein -
O2U05_RS00705 (O2U05_00700) 122083..122286 + 204 WP_283558371.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..144347 144347


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266669 WP_044006010.1 NZ_CP114518:117053-117304 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266669 WP_044006009.1 NZ_CP114518:116794-117060 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References