Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 116794..117304 Replicon plasmid unnamed1
Accession NZ_CP114518
Organism Ligilactobacillus salivarius strain S91

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U05_RS00675 Protein ID WP_044006010.1
Coordinates 117053..117304 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U05_RS00670 Protein ID WP_044006009.1
Coordinates 116794..117060 (+) Length 89 a.a.

Genomic Context

O2U05_RS00645O2U05_RS00650O2U05_RS00655O2U05_RS00660O2U05_RS00665O2U05_RS00670O2U05_RS00675O2U05_RS00690O2U05_RS00695O2U05_RS00700O2U05_RS00705O2U05_RS00680O2U05_RS00685
Location: 112708..113499 (792 bp)
Type: Others
Protein ID: WP_283558368.1
Location: 113541..113939 (399 bp)
Type: Others
Protein ID: WP_283558379.1
Location: 114060..114473 (414 bp)
Type: Others
Protein ID: WP_283475116.1
Location: 114577..114963 (387 bp)
Type: Others
Protein ID: WP_283475114.1
Location: 115110..115445 (336 bp)
Type: Others
Protein ID: WP_283475113.1
Location: 116794..117060 (267 bp)
Type: Antitoxin
Protein ID: WP_044006009.1
Location: 117053..117304 (252 bp)
Type: Toxin
Protein ID: WP_044006010.1
Location: 119177..120274 (1098 bp)
Type: Others
Protein ID: WP_044006012.1
Location: 120283..120567 (285 bp)
Type: Others
Protein ID: WP_283558370.1
Location: 121126..121977 (852 bp)
Type: Others
Protein ID: WP_283475147.1
Location: 122083..122286 (204 bp)
Type: Others
Protein ID: WP_283558371.1
Location: 117959..118366 (408 bp)
Type: Others
Protein ID: WP_283558369.1
Location: 118546..118863 (318 bp)
Type: Others
Protein ID: WP_283548105.1
ToxinAntitoxinOther genes
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Locus tag
Coordinates
Strand
Size (bp)
Protein ID
Product
Description
O2U05_RS00645 (O2U05_00640)112708..113499+792WP_283558368.1replication initiation protein-
O2U05_RS00650 (O2U05_00645)113541..113939+399WP_283558379.1hypothetical protein-
O2U05_RS00655 (O2U05_00650)114060..114473+414WP_283475116.1hypothetical protein-
O2U05_RS00660 (O2U05_00655)114577..114963+387WP_283475114.1hypothetical protein-
O2U05_RS00665 (O2U05_00660)115110..115445+336WP_283475113.1hypothetical protein-
O2U05_RS00670 (O2U05_00665)116794..117060+267WP_044006009.1type II toxin-antitoxin system Phd/YefM family antitoxinAntitoxin
O2U05_RS00675 (O2U05_00670)117053..117304+252WP_044006010.1Txe/YoeB family addiction module toxinToxin
O2U05_RS00680 (O2U05_00675)117959..118366-408WP_283558369.1hypothetical protein-
O2U05_RS00685 (O2U05_00680)118546..118863-318WP_283548105.1hypothetical protein-
O2U05_RS00690 (O2U05_00685)119177..120274+1098WP_044006012.1ParM/StbA family protein-
O2U05_RS00695 (O2U05_00690)120283..120567+285WP_283558370.1hypothetical protein-
O2U05_RS00700 (O2U05_00695)121126..121977+852WP_283475147.1hypothetical protein-
O2U05_RS00705 (O2U05_00700)122083..122286+204WP_283558371.1hypothetical protein-

Associated MGEs

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MGE
detail
Similar
MGEs
Relative
position
MGE Type
Cargo ARG
Virulence gene
Coordinates
Length (bp)
-insideNon-Mobilizable plasmid--1..144347144347


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266669 WP_044006010.1 NZ_CP114518:117053-117304 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266669 WP_044006009.1 NZ_CP114518:116794-117060 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found
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Protein
Organism
Identities (%)
Coverage (%)
Ha-value
No matching records found

Structures

Toxin

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Source
ID
Structure
No matching records found

Antitoxin

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Source
ID
Structure
No matching records found

References