Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 113990..114500 Replicon plasmid unnamed2
Accession NZ_CP114514
Organism Ligilactobacillus salivarius strain S39

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U03_RS11165 Protein ID WP_044006010.1
Coordinates 113990..114241 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U03_RS11170 Protein ID WP_044006009.1
Coordinates 114234..114500 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U03_RS11145 (O2U03_11145) 109314..110165 - 852 WP_283475147.1 hypothetical protein -
O2U03_RS11150 (O2U03_11150) 110611..111009 - 399 WP_087250758.1 hypothetical protein -
O2U03_RS11155 (O2U03_11155) 111018..112115 - 1098 WP_044006012.1 ParM/StbA family protein -
O2U03_RS11160 (O2U03_11160) 112429..113541 + 1113 WP_283548149.1 hypothetical protein -
O2U03_RS11165 (O2U03_11165) 113990..114241 - 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U03_RS11170 (O2U03_11170) 114234..114500 - 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U03_RS11175 (O2U03_11175) 114595..114930 - 336 WP_283475111.1 hypothetical protein -
O2U03_RS11180 (O2U03_11180) 115849..116184 - 336 WP_283475113.1 hypothetical protein -
O2U03_RS11185 (O2U03_11185) 116330..116689 - 360 WP_283475502.1 hypothetical protein -
O2U03_RS11190 (O2U03_11190) 116819..117232 - 414 WP_283475116.1 hypothetical protein -
O2U03_RS11195 (O2U03_11195) 117352..118584 - 1233 WP_283475118.1 RepB family plasmid replication initiator protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..126456 126456


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266667 WP_044006010.1 NZ_CP114514:c114241-113990 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266667 WP_044006009.1 NZ_CP114514:c114500-114234 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References