Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 98874..99384 Replicon plasmid unnamed2
Accession NZ_CP114514
Organism Ligilactobacillus salivarius strain S39

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U03_RS11090 Protein ID WP_044006010.1
Coordinates 99133..99384 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U03_RS11085 Protein ID WP_044006009.1
Coordinates 98874..99140 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U03_RS11060 (O2U03_11060) 94786..96018 + 1233 WP_283475118.1 RepB family plasmid replication initiator protein -
O2U03_RS11065 (O2U03_11065) 96139..96552 + 414 WP_283475116.1 hypothetical protein -
O2U03_RS11070 (O2U03_11070) 96683..97042 + 360 WP_283475502.1 hypothetical protein -
O2U03_RS11075 (O2U03_11075) 97189..97524 + 336 WP_283475113.1 hypothetical protein -
O2U03_RS11080 (O2U03_11080) 98444..98779 + 336 WP_283475111.1 hypothetical protein -
O2U03_RS11085 (O2U03_11085) 98874..99140 + 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U03_RS11090 (O2U03_11090) 99133..99384 + 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U03_RS11095 (O2U03_11095) 99840..100946 - 1107 WP_283475109.1 hypothetical protein -
O2U03_RS11100 (O2U03_11100) 101261..102358 + 1098 WP_044006012.1 ParM/StbA family protein -
O2U03_RS11105 (O2U03_11105) 102367..102765 + 399 WP_087250758.1 hypothetical protein -
O2U03_RS11110 (O2U03_11110) 103211..104062 + 852 WP_283475147.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..126456 126456


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266666 WP_044006010.1 NZ_CP114514:99133-99384 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266666 WP_044006009.1 NZ_CP114514:98874-99140 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References