Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 33932..34442 Replicon plasmid unnamed5
Accession NZ_CP114508
Organism Ligilactobacillus salivarius strain S32

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U01_RS11280 Protein ID WP_044006010.1
Coordinates 33932..34183 (-) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U01_RS11285 Protein ID WP_044006009.1
Coordinates 34176..34442 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U01_RS11260 (O2U01_11265) 29254..30105 - 852 WP_283475147.1 hypothetical protein -
O2U01_RS11265 (O2U01_11270) 30551..30949 - 399 WP_087250758.1 hypothetical protein -
O2U01_RS11270 (O2U01_11275) 30958..32055 - 1098 WP_044006012.1 ParM/StbA family protein -
O2U01_RS11275 (O2U01_11280) 32370..33476 + 1107 WP_283475109.1 hypothetical protein -
O2U01_RS11280 (O2U01_11285) 33932..34183 - 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U01_RS11285 (O2U01_11290) 34176..34442 - 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U01_RS11290 (O2U01_11295) 34537..34872 - 336 WP_283475111.1 hypothetical protein -
O2U01_RS11295 (O2U01_11300) 35792..36127 - 336 WP_283475113.1 hypothetical protein -
O2U01_RS11300 (O2U01_11305) 36274..36660 - 387 WP_283475114.1 hypothetical protein -
O2U01_RS11305 (O2U01_11310) 36764..37177 - 414 WP_283475116.1 hypothetical protein -
O2U01_RS11310 (O2U01_11315) 37298..38530 - 1233 WP_283475118.1 RepB family plasmid replication initiator protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..61694 61694


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266664 WP_044006010.1 NZ_CP114508:c34183-33932 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266664 WP_044006009.1 NZ_CP114508:c34442-34176 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References