Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Txe-Axe/YoeB-RelB
Location 18822..19332 Replicon plasmid unnamed5
Accession NZ_CP114508
Organism Ligilactobacillus salivarius strain S32

Toxin (Protein)


Gene name Txe Uniprot ID -
Locus tag O2U01_RS11185 Protein ID WP_044006010.1
Coordinates 19081..19332 (+) Length 84 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag O2U01_RS11180 Protein ID WP_044006009.1
Coordinates 18822..19088 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O2U01_RS11155 (O2U01_11160) 14737..15773 + 1037 Protein_21 RepB family plasmid replication initiator protein -
O2U01_RS11160 (O2U01_11165) 16089..16502 + 414 WP_283475116.1 hypothetical protein -
O2U01_RS11165 (O2U01_11170) 16606..16992 + 387 WP_283475114.1 hypothetical protein -
O2U01_RS11170 (O2U01_11175) 17139..17474 + 336 WP_283475113.1 hypothetical protein -
O2U01_RS11175 (O2U01_11180) 18392..18727 + 336 WP_283475111.1 hypothetical protein -
O2U01_RS11180 (O2U01_11185) 18822..19088 + 267 WP_044006009.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
O2U01_RS11185 (O2U01_11190) 19081..19332 + 252 WP_044006010.1 Txe/YoeB family addiction module toxin Toxin
O2U01_RS11190 (O2U01_11195) 19788..20894 - 1107 WP_283475109.1 hypothetical protein -
O2U01_RS11195 (O2U01_11200) 21208..22305 + 1098 WP_044006012.1 ParM/StbA family protein -
O2U01_RS11200 (O2U01_11205) 22314..22712 + 399 WP_087250758.1 hypothetical protein -
O2U01_RS11205 (O2U01_11210) 23156..23914 + 759 WP_283475130.1 hypothetical protein -
O2U01_RS11210 (O2U01_11215) 23872..24006 + 135 WP_283475131.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Non-Mobilizable plasmid - - 1..61694 61694


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(1-83)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-55)


Sequences

Toxin        


Download         Length: 84 a.a.        Molecular weight: 10098.41 Da        Isoelectric Point: 8.4252

>T266663 WP_044006010.1 NZ_CP114508:19081-19332 [Ligilactobacillus salivarius]
MNKNWSDEAWDDYMSWQSDKRIVKKINKLIKDIDRHPFSGIGKPEPLKYGLSGTWSRRITEEHRIVYEIKDDEIRIYSVR
DHY

Download         Length: 252 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10412.63 Da        Isoelectric Point: 4.5967

>AT266663 WP_044006009.1 NZ_CP114508:18822-19088 [Ligilactobacillus salivarius]
MEATTYSNFRKSLKSFMKQVNEDSEPLIVTNKNKEEDIVVMGKDDYDSLVETMRIIENKYLYNKIRRGREQLDSKSNYHD
LIEVDGDE

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References