Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relE-yefM/YoeB-RelB
Location 1206438..1206946 Replicon chromosome
Accession NZ_CP114372
Organism Aeromicrobium sp. HA

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag O3S82_RS05905 Protein ID WP_269306281.1
Coordinates 1206686..1206946 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name yefM Uniprot ID -
Locus tag O3S82_RS05900 Protein ID WP_269306280.1
Coordinates 1206438..1206689 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3S82_RS05870 1201713..1203218 + 1506 WP_269306270.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatA -
O3S82_RS05875 1203215..1204735 + 1521 WP_269306272.1 Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase subunit GatB -
O3S82_RS05880 1204829..1205119 + 291 WP_179425372.1 DUF1540 domain-containing protein -
O3S82_RS05885 1205167..1205646 + 480 WP_269306274.1 pyridoxamine 5'-phosphate oxidase family protein -
O3S82_RS05890 1205657..1205905 - 249 WP_179425368.1 hypothetical protein -
O3S82_RS05895 1205902..1206297 - 396 WP_269306277.1 hypothetical protein -
O3S82_RS05900 1206438..1206689 + 252 WP_269306280.1 type II toxin-antitoxin system prevent-host-death family antitoxin Antitoxin
O3S82_RS05905 1206686..1206946 + 261 WP_269306281.1 Txe/YoeB family addiction module toxin Toxin
O3S82_RS05910 1206959..1207333 - 375 WP_269306283.1 hypothetical protein -
O3S82_RS05915 1207412..1207948 + 537 WP_269306285.1 hypothetical protein -
O3S82_RS05920 1208018..1208962 + 945 WP_269306287.1 DUF2510 domain-containing protein -
O3S82_RS05925 1208959..1209345 - 387 WP_179425358.1 nuclear transport factor 2 family protein -
O3S82_RS05930 1209364..1211886 - 2523 WP_269306290.1 ATP-dependent helicase HrpB -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-74)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10366.73 Da        Isoelectric Point: 8.0396

>T266632 WP_269306281.1 NZ_CP114372:1206686-1206946 [Aeromicrobium sp. HA]
MSIVFSTAAWDDYLWWQQQDRKVLKRINVLIRDIERNGNEGIGKPEPLKHGFQGYWSRRITDEHRLVYKIVDEDVRIAAC
RYHYSD

Download         Length: 261 bp

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9414.46 Da        Isoelectric Point: 4.2503

>AT266632 WP_269306280.1 NZ_CP114372:1206438-1206689 [Aeromicrobium sp. HA]
MRTMSYSESRRRYAEVLDAVVDDREEVVITRAGHEPAVIVSLDDYESLKETAYLLRSPANARRLLGSIEELEAEQGTSQE
LLD

Download         Length: 252 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References