Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) vapBC/VapC(toxin)
Location 820725..821353 Replicon chromosome
Accession NZ_CP114372
Organism Aeromicrobium sp. HA

Toxin (Protein)


Gene name vapC Uniprot ID -
Locus tag O3S82_RS04005 Protein ID WP_269305683.1
Coordinates 820725..821120 (-) Length 132 a.a.

Antitoxin (Protein)


Gene name vapB Uniprot ID -
Locus tag O3S82_RS04010 Protein ID WP_269305685.1
Coordinates 821117..821353 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O3S82_RS03995 816729..819857 + 3129 WP_269305680.1 ATP-dependent DNA helicase -
O3S82_RS04000 819861..820724 + 864 WP_269305682.1 NAD(+) diphosphatase -
O3S82_RS04005 820725..821120 - 396 WP_269305683.1 type II toxin-antitoxin system VapC family toxin Toxin
O3S82_RS04010 821117..821353 - 237 WP_269305685.1 type II toxin-antitoxin system VapB family antitoxin Antitoxin
O3S82_RS04015 821399..821644 - 246 WP_269305687.1 mycoredoxin -
O3S82_RS04020 821796..823787 + 1992 WP_269305689.1 3'-5' exonuclease -
O3S82_RS04025 823791..825152 - 1362 WP_269305691.1 AarF/ABC1/UbiB kinase family protein -
O3S82_RS04030 825189..825980 - 792 WP_179425888.1 hypothetical protein -
O3S82_RS04035 826077..826235 - 159 WP_179425886.1 DUF5679 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

PIN domain

(1-123)

Antitoxin

Antitoxin VapB-like

(1-77)


Sequences

Toxin        


Download         Length: 132 a.a.        Molecular weight: 14185.96 Da        Isoelectric Point: 4.4840

>T266631 WP_269305683.1 NZ_CP114372:c821120-820725 [Aeromicrobium sp. HA]
VIVDTSAVVAVIKREAGWEAIDRALAAATTPRMSAGTQLELGIVVDQARDPELSRLVDALLRDWSVEIEPVTAEHARIAR
EAYRDYGRGSGHRARLNYGDCFAYALASQSGEPLLYVGDDFAATDLTPVLV

Download         Length: 396 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8639.67 Da        Isoelectric Point: 5.0760

>AT266631 WP_269305685.1 NZ_CP114372:c821353-821117 [Aeromicrobium sp. HA]
MALNIKNERVHALAREVAQRTGRTQTSAIEFALERLLANLGDSSAAIARRQRIEHVQDLAVNADLDAEDLYDEAGLPR

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References