Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2040663..2040807 Replicon chromosome
Accession NZ_CP114361
Organism Klebsiella variicola strain 2022CK-00568

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2040699..2040801 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2040663..2040807 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OPU52_RS09870 (OPU52_09870) 2035793..2037853 + 2061 WP_071582979.1 oligopeptidase B -
OPU52_RS09875 (OPU52_09875) 2037857..2038516 - 660 WP_008804267.1 exodeoxyribonuclease X -
OPU52_RS09880 (OPU52_09880) 2038595..2038825 - 231 WP_012541260.1 DNA polymerase III subunit theta -
OPU52_RS09885 (OPU52_09885) 2038939..2039313 + 375 WP_016161388.1 CopC domain-containing protein YobA -
OPU52_RS09890 (OPU52_09890) 2039317..2040186 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
OPU52_RS09895 (OPU52_09895) 2040203..2040541 + 339 WP_008804271.1 YebY family protein -
- 2040663..2040807 - 145 - - Antitoxin
- 2040699..2040801 + 103 - - Toxin
OPU52_RS09900 (OPU52_09900) 2041186..2041329 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
OPU52_RS09905 (OPU52_09905) 2041433..2042401 - 969 WP_162493241.1 VirK/YbjX family protein -
OPU52_RS09910 (OPU52_09910) 2042558..2043211 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
OPU52_RS09915 (OPU52_09915) 2043208..2043399 - 192 WP_002911395.1 YebW family protein -
OPU52_RS09920 (OPU52_09920) 2043497..2043736 - 240 WP_002911393.1 YebV family protein -
OPU52_RS09925 (OPU52_09925) 2043852..2045285 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T266616 NZ_CP114361:2040699-2040801 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT266616 NZ_CP114361:c2040807-2040663 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References