Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2039464..2039608 Replicon chromosome
Accession NZ_CP114312
Organism Klebsiella variicola strain 2022CK-00500

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2039500..2039602 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2039464..2039608 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEE47_RS09860 (OEE47_09860) 2034594..2036654 + 2061 WP_071582979.1 oligopeptidase B -
OEE47_RS09865 (OEE47_09865) 2036658..2037317 - 660 WP_008804267.1 exodeoxyribonuclease X -
OEE47_RS09870 (OEE47_09870) 2037396..2037626 - 231 WP_012541260.1 DNA polymerase III subunit theta -
OEE47_RS09875 (OEE47_09875) 2037740..2038114 + 375 WP_016161388.1 CopC domain-containing protein YobA -
OEE47_RS09880 (OEE47_09880) 2038118..2038987 + 870 WP_012541262.1 copper homeostasis membrane protein CopD -
OEE47_RS09885 (OEE47_09885) 2039004..2039342 + 339 WP_008804271.1 YebY family protein -
- 2039464..2039608 - 145 - - Antitoxin
- 2039500..2039602 + 103 - - Toxin
OEE47_RS09890 (OEE47_09890) 2039987..2040130 - 144 WP_048268691.1 Ecr family regulatory small membrane protein -
OEE47_RS09895 (OEE47_09895) 2040234..2041202 - 969 WP_162493241.1 VirK/YbjX family protein -
OEE47_RS09900 (OEE47_09900) 2041359..2042012 + 654 WP_008804273.1 protein-serine/threonine phosphatase -
OEE47_RS09905 (OEE47_09905) 2042009..2042200 - 192 WP_002911395.1 YebW family protein -
OEE47_RS09910 (OEE47_09910) 2042298..2042537 - 240 WP_002911393.1 YebV family protein -
OEE47_RS09915 (OEE47_09915) 2042653..2044086 - 1434 WP_008804274.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T266483 NZ_CP114312:2039500-2039602 [Klebsiella variicola]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 145 bp

>AT266483 NZ_CP114312:c2039608-2039464 [Klebsiella variicola]
ACCGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGT
TGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References