Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 926179..926836 Replicon chromosome
Accession NZ_CP114308
Organism Klebsiella oxytoca strain 2022CK-00499

Toxin (Protein)


Gene name cptA Uniprot ID A0A181X6I0
Locus tag OEE41_RS04430 Protein ID WP_004105559.1
Coordinates 926426..926836 (+) Length 137 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A285B945
Locus tag OEE41_RS04425 Protein ID WP_004105561.1
Coordinates 926179..926445 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OEE41_RS04410 (OEE41_04410) 921432..921857 - 426 WP_004124962.1 PTS sugar transporter subunit IIA -
OEE41_RS04415 (OEE41_04415) 921978..924776 - 2799 WP_210614839.1 transcriptional regulator DagR -
OEE41_RS04420 (OEE41_04420) 924952..925935 - 984 WP_004115279.1 tRNA-modifying protein YgfZ -
OEE41_RS04425 (OEE41_04425) 926179..926445 + 267 WP_004105561.1 FAD assembly factor SdhE Antitoxin
OEE41_RS04430 (OEE41_04430) 926426..926836 + 411 WP_004105559.1 protein YgfX Toxin
OEE41_RS04435 (OEE41_04435) 926845..927366 - 522 WP_210614837.1 flavodoxin FldB -
OEE41_RS04440 (OEE41_04440) 927488..928384 + 897 WP_004105555.1 site-specific tyrosine recombinase XerD -
OEE41_RS04445 (OEE41_04445) 928407..929120 + 714 WP_004105554.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
OEE41_RS04450 (OEE41_04450) 929126..930859 + 1734 WP_004105553.1 single-stranded-DNA-specific exonuclease RecJ -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-132)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 137 a.a.        Molecular weight: 16061.83 Da        Isoelectric Point: 10.9455

>T266468 WP_004105559.1 NZ_CP114308:926426-926836 [Klebsiella oxytoca]
VVLWQSDLRISWRAQWFSLLMHGVVAALVLVLPWPLSYTPLWLILLSLVVFDCVRSQRRIHARQGEIKLLIDSRLRWQKA
EWDIVGTPWVINSGMLLRLRNTENQRTQHLWVAADSMDAGEWRDLRRLVLQKPTQD

Download         Length: 411 bp

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10555.02 Da        Isoelectric Point: 5.1498

>AT266468 WP_004105561.1 NZ_CP114308:926179-926445 [Klebsiella oxytoca]
MDINNKARIHWACRRGMRELDISIMPFFEHEYDTLSDDDKRLFIRLLENDDPDLFNWLMNHGEPADAELQRMVKLIQTRN
RERGPVAI

Download         Length: 267 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A181X6I0

Antitoxin

Source ID Structure
AlphaFold DB A0A285B945

References