Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2181713..2181858 Replicon chromosome
Accession NZ_CP114305
Organism Klebsiella oxytoca strain 2022CK-00498

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2181748..2181851 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2181713..2181858 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OGU21_RS10245 (OGU21_10250) 2176817..2178877 + 2061 WP_032726355.1 oligopeptidase B -
OGU21_RS10250 (OGU21_10255) 2178884..2179543 - 660 WP_004103360.1 exodeoxyribonuclease X -
OGU21_RS10255 (OGU21_10260) 2179622..2179852 - 231 WP_004103351.1 DNA polymerase III subunit theta -
OGU21_RS10260 (OGU21_10265) 2179988..2180362 + 375 WP_016808306.1 CopC domain-containing protein YobA -
OGU21_RS10265 (OGU21_10270) 2180367..2181236 + 870 WP_004103346.1 copper homeostasis membrane protein CopD -
OGU21_RS10270 (OGU21_10275) 2181253..2181591 + 339 WP_004103344.1 YebY family protein -
- 2181713..2181858 - 146 - - Antitoxin
- 2181748..2181851 + 104 - - Toxin
OGU21_RS10275 (OGU21_10280) 2181978..2182937 - 960 WP_269776869.1 spore coat protein U domain-containing protein -
OGU21_RS10280 (OGU21_10285) 2182949..2185282 - 2334 WP_269776870.1 fimbria/pilus outer membrane usher protein -
OGU21_RS10285 (OGU21_10290) 2185285..2185992 - 708 WP_269776871.1 fimbria/pilus periplasmic chaperone -
OGU21_RS10290 (OGU21_10295) 2186067..2186585 - 519 WP_032692328.1 spore coat U domain-containing protein -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T266460 NZ_CP114305:2181748-2181851 [Klebsiella oxytoca]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTTTTTTT

Antitoxin


Download         Length: 146 bp

>AT266460 NZ_CP114305:c2181858-2181713 [Klebsiella oxytoca]
AAAAGATAAAAAAAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTTACCGTGTCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References