Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE-HTH
Location 1812509..1813187 Replicon chromosome
Accession NZ_CP114281
Organism Gallibacterium anatis strain ESV200

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CF557_RS08530 Protein ID WP_094872202.1
Coordinates 1812804..1813187 (-) Length 128 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CF557_RS08525 Protein ID WP_013746372.1
Coordinates 1812509..1812811 (-) Length 101 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CF557_RS08500 (CF557_08500) 1807874..1808593 + 720 WP_039162542.1 DUF969 domain-containing protein -
CF557_RS08505 (CF557_08505) 1808593..1809576 + 984 WP_021462390.1 DUF979 domain-containing protein -
CF557_RS08510 (CF557_08510) 1809586..1810578 + 993 WP_094872206.1 DUF2891 domain-containing protein -
CF557_RS08515 (CF557_08515) 1810989..1811705 + 717 WP_039169016.1 amino acid ABC transporter permease -
CF557_RS08520 (CF557_08520) 1811708..1812451 + 744 WP_179256211.1 amino acid ABC transporter ATP-binding protein -
CF557_RS08525 (CF557_08525) 1812509..1812811 - 303 WP_013746372.1 DNA-binding transcriptional regulator Antitoxin
CF557_RS08530 (CF557_08530) 1812804..1813187 - 384 WP_094872202.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CF557_RS08535 (CF557_08535) 1813387..1813665 + 279 WP_039089572.1 type II toxin-antitoxin system RelE/ParE family toxin -
CF557_RS08540 (CF557_08540) 1813676..1813972 + 297 WP_018346511.1 HigA family addiction module antitoxin -
CF557_RS08545 (CF557_08545) 1814003..1814590 - 588 WP_018346512.1 Fic family protein -
CF557_RS08550 (CF557_08550) 1814559..1814750 - 192 WP_013746378.1 antitoxin VbhA family protein -
CF557_RS08555 (CF557_08555) 1815235..1816065 - 831 Protein_1664 IS3 family transposase -
CF557_RS08560 (CF557_08560) 1816068..1816373 - 306 WP_013744838.1 IS3 family transposase -
CF557_RS08565 (CF557_08565) 1816741..1818120 - 1380 WP_094872855.1 cysteine--tRNA ligase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(1-120)

Antitoxin

Cro/C1-type helix-turn-helix domain

(45-88)


Sequences

Toxin        


Download         Length: 128 a.a.        Molecular weight: 14285.31 Da        Isoelectric Point: 8.9256

>T266451 WP_094872202.1 NZ_CP114281:c1813187-1812804 [Gallibacterium anatis]
MRIFKTKAFNKFALKNGIPDSELINAITRAEQGLIDADLGSNIIKQRIARKGQVRSGGFRSFIFYCIQNNSYFVAGISKN
DRENISSQELAALKALAREYTRLTAKQIEAQIENGLFIEILPEAEDE

Download         Length: 384 bp

Antitoxin


Download         Length: 101 a.a.        Molecular weight: 11270.16 Da        Isoelectric Point: 7.3581

>AT266451 WP_013746372.1 NZ_CP114281:c1812811-1812509 [Gallibacterium anatis]
MSELLAMIHENAADLHKAGIINKKTMKEFDQLCLTPVVTYTPDEIRAIREKEQVSQAVFAHYLNVSKNMISEWERGVKKP
SGAALKLLNLVQHNGIEILV

Download         Length: 303 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References