Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-DnaT
Location 1236531..1237080 Replicon chromosome
Accession NZ_CP114281
Organism Gallibacterium anatis strain ESV200

Toxin (Protein)


Gene name relE Uniprot ID F4HEY3
Locus tag CF557_RS05830 Protein ID WP_013746900.1
Coordinates 1236781..1237080 (+) Length 100 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0A2YRY5
Locus tag CF557_RS05825 Protein ID WP_039085646.1
Coordinates 1236531..1236791 (+) Length 87 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CF557_RS05810 (CF557_05810) 1231807..1232871 - 1065 WP_269445961.1 dTDP-glucose 4,6-dehydratase -
CF557_RS05815 (CF557_05815) 1233186..1234613 + 1428 WP_269445962.1 undecaprenyl-phosphate galactose phosphotransferase WbaP -
CF557_RS05820 (CF557_05820) 1234686..1236245 - 1560 WP_094871709.1 Fic family protein -
CF557_RS05825 (CF557_05825) 1236531..1236791 + 261 WP_039085646.1 stability protein StbD Antitoxin
CF557_RS05830 (CF557_05830) 1236781..1237080 + 300 WP_013746900.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CF557_RS05835 (CF557_05835) 1237207..1237425 + 219 WP_013746899.1 translation initiation factor IF-1 -
CF557_RS05840 (CF557_05840) 1237511..1238779 + 1269 WP_094871712.1 O-antigen ligase -
CF557_RS05845 (CF557_05845) 1238820..1238981 - 162 WP_179256201.1 hypothetical protein -
CF557_RS05850 (CF557_05850) 1239182..1240300 - 1119 WP_094871715.1 iron-sulfur cluster carrier protein ApbC -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-85)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 100 a.a.        Molecular weight: 11752.61 Da        Isoelectric Point: 10.4596

>T266449 WP_013746900.1 NZ_CP114281:1236781-1237080 [Gallibacterium anatis]
MTYSLQFHEKALKEWKKLDETTRSQLKKKLAERLQNPHIQADRLSGFSNPTYKIKLRSIGYRLVYEVNDDIITVFVLSVG
KRNKLQAYINAHHRAEKMY

Download         Length: 300 bp

Antitoxin


Download         Length: 87 a.a.        Molecular weight: 9928.42 Da        Isoelectric Point: 6.7176

>AT266449 WP_039085646.1 NZ_CP114281:1236531-1236791 [Gallibacterium anatis]
MKNVHKIHTDVVASITSLKRDPMRTIYNDTGSQAVAILNRNQPAFYCITPELFEHFLELEENAELAKIVQERKKEGKFIK
VNIDDL

Download         Length: 261 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB F4HEY3

Antitoxin

Source ID Structure
AlphaFold DB A0A0A2YRY5

References