266444

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4115142..4115695 Replicon chromosome
Accession NZ_CP114280
Organism Dickeya lacustris strain LMG30899

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag O1Q98_RS18670 Protein ID WP_125260002.1
Coordinates 4115381..4115695 (+) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag O1Q98_RS18665 Protein ID WP_125260001.1
Coordinates 4115142..4115378 (+) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
O1Q98_RS18655 (O1Q98_18660) 4112721..4113565 + 845 WP_278142462.1 IS5 family transposase -
O1Q98_RS18660 (O1Q98_18665) 4113879..4114823 + 945 WP_125260000.1 zincin-like metallopeptidase domain-containing protein -
O1Q98_RS18665 (O1Q98_18670) 4115142..4115378 + 237 WP_125260001.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
O1Q98_RS18670 (O1Q98_18675) 4115381..4115695 + 315 WP_125260002.1 CcdB family protein Toxin
O1Q98_RS18675 (O1Q98_18680) 4116106..4116816 + 711 WP_240632785.1 hypothetical protein -
O1Q98_RS18680 (O1Q98_18685) 4117009..4117860 - 852 WP_205744273.1 hypothetical protein -
O1Q98_RS18685 (O1Q98_18690) 4117854..4119500 - 1647 WP_125260003.1 AAA family ATPase -
O1Q98_RS18690 (O1Q98_18695) 4119541..4120648 + 1108 Protein_3636 IS3-like element ISKpn20 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4098668..4126596 27928
- flank IS/Tn - - 4112832..4113170 338


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11563.53 Da        Isoelectric Point: 7.9859

>T266444 WP_125260002.1 NZ_CP114280:4115381-4115695 [Dickeya lacustris]
MQFTVYGNTGKSAIYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVRLTDGKEYAVMTHELASIPVQALG
TVFCDALQYRSQVKAAIDFLIDGF

Download         Length: 315 bp

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8999.00 Da        Isoelectric Point: 6.4631

>AT266444 WP_125260001.1 NZ_CP114280:4115142-4115378 [Dickeya lacustris]
MTAKQRNTQSVTMTVERGLLVRAREAGINLSATLSTALDAELRRHEAKKWQEENREAIDALNRFHDENGCFSDEYRTF

Download         Length: 237 bp


Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References